Evidence map›Paper›PMID 28911790›Full record

ReviewPlacenta2017

Microchimerism: Defining and redefining the prepregnancy context - A review.

H S Gammill, W E Harrington

Abstract readReview
In one paragraph

Review in Placenta, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Identifying Key Questions and Challenges in Microchimerism Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. The Microchimerism Literature Atlas.Bioinformatics and biology insights · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Umbilical Cord Maternal Microchimerism in Normal and Preeclampsia Pregnancies.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Observational
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H S GammillDepartment of Obstetrics and Gynecology, University of Washington, United States; Clinical Research Division, Fred Hutchinson Cancer Research Center, United States. Electronic address: hgammill@uw.edu.
W E HarringtonDepartment of Pediatrics, University of Washington and Seattle Children's Hospital, United States.

Funding

ACADEMIC PEDIATRIC INFECTIOUS DISEASET32HD007233 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI KEVIN B URDAHL · 1985 to 2026
$6.7M
The Maternal Anti-fetal Immune Response & Role of Microchimerism in PreeclamsiaK08HD067221 · NICHD · UNIVERSITY OF WASHINGTON · PI GAMMILL, HILARY SEGLIN · 2012 to 2016
$644k
NICHD NIH HHS K08 HD067221NICHD NIH HHS T32 HD007233
6 · The paper itself

Abstract

Bidirectional transplacental exchange characterizes human pregnancy. Cells exchanged between mother and fetus can durably persist as microchimerism and may have both short- and long-term consequences for the recipient. The amount, type, and persistence of microchimerism are influenced by obstetric characteristics, pregnancy complications, exposures to infection, and other factors. A reproductive-aged woman enters pregnancy harboring previously acquired microchimeric "grafts," which may influence her preconception health and her subsequent pregnancy outcomes. Many questions remain to be answered about microchimerism with broad-ranging implications. This review will summarize key aspects of this field of research and propose important questions to be addressed moving forward.

Indexed as

ChimerismMaternal-Fetal ExchangeFemaleFetusHumansMalariaPlacenta DiseasesPregnancyMaternal-fetal exchangeMicrochimerismPlacental malariaPreeclampsiaReproductive immunology

Identifiers

PMID28911790
PMCPMC5718967

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.