Evidence map›Paper›PMID 28911649›Full record

ArticleJournal of food and drug analysis2017

Long-chain bases from sea cucumber mitigate endoplasmic reticulum stress and inflammation in obesity mice.

Shiwei Hu, Jinhui Wang, Jingfeng Wang, Changhu Xue, Yuming Wang

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shiwei HuInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhejiang Province, China.
Jinhui WangInnovation Application Institute, Zhejiang Ocean University, Zhoushan, Zhejiang Province, China.
Jingfeng WangCollege of Food Science and Engineering, Ocean University of China, Qingdao, Shandong Province, China.
Changhu XueCollege of Food Science and Engineering, Ocean University of China, Qingdao, Shandong Province, China.
Yuming WangCollege of Food Science and Engineering, Ocean University of China, Qingdao, Shandong Province, China.
Ocean University of China · CNZhejiang Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoplasmic reticulum (ER) stress and inflammation can induce hyperglycemia. Long-chain bases (LCBs) from sea cucumber exhibit antihyperglycemic activities. However, their effects on ER stress and inflammation are unknown. We investigated the effects of LCBs on ER stress and inflammatory response in high-fat, fructose diet-induced obesity mice. Reactive oxygen species and free fatty acids were measured. Inflammatory cytokines in serum and their mRNA expressions in epididymal adipose tissues were investigated. Hepatic ER stress-related key genes were detected. c-Jun NH

Indexed as

Endoplasmic Reticulum StressSea CucumbersAnimalsInflammationMiceMice, ObeseObesitycytokinesendoplasmic reticulum stressinflammationlong-chain basessea cucumber

Identifiers

PMID28911649
PMCPMC9328807
OpenAlexW2558669891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.