ArticleJournal of food and drug analysis2017
Cytotoxic and antioxidant capacity of camel milk peptides: Effects of isolated peptide on superoxide dismutase and catalase gene expression.
Article in Journal of food and drug analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- The Desert Duo: A Narrative Review on How Camel Milk and Date Fruits Combat Oxidative Stress and Enhance Metabolic Health.Antioxidants (Basel, Switzerland) · 2026Review
- Camel Whey protein ameliorates type Ⅰ diabetic cardiomyopathy by mitigating oxidative stress, inflammation and apoptosis.Food science of animal resources · 2026Article
- Valorization of camel milk into probiotic-fermented high-energy beverages incorporating Khalas date and nuts: nutritional quality and bioactives profiling.Frontiers in nutrition · 2026Article
- A comparative study of flaxseed gum effect on Lactobacillus acidophilus genes expression, and textural, sensory, structural, and microbiological properties of synbiotic Iranian white cheese.Scientific reports · 2025Article
- Freeze-Dried Probiotic Fermented Camel Milk Enriched with Ajwa Date Pulp: Evaluation of Functional Properties, Probiotic Viability, and In Vitro Antidiabetic and Anticancer Activities.Foods (Basel, Switzerland) · 2025Article
- Applications of bioactive peptides in cosmeceuticals: a review.Journal of Zhejiang University. Science. B · 2025Review
- Article
- Bioactive Milk Peptides as a Nutraceutical Opportunity and Challenges.Current protein & peptide science · 2025Review
- Ultrasound-assisted extraction and antioxidant activity of polysaccharides from Tenebrio molitor.Scientific reports · 2024Article
- Selenium-Chelating Peptide Derived from Wheat Gluten:Foods (Basel, Switzerland) · 2024Article
- Milk and Its Derivatives as Sources of Components and Microorganisms with Health-Promoting Properties: Probiotics and Bioactive Peptides.Foods (Basel, Switzerland) · 2024Review
- The effects of camel milk in systemic inflammation and oxidative stress of cigarette smoke-induced chronic obstructive pulmonary disease model in rat.Frontiers in veterinary science · 2024Article
- Glycine-rich peptides from fermented Chenopodium formosanum sprout as an antioxidant to modulate the oxidative stress.Journal of food and drug analysis · 2023Article
- Synthesis and biological evaluation of capsaicin analogues as antioxidant and neuroprotective agents.RSC advances · 2023Article
- Antibacterial, Antifungal, and Anticancer Effects of Camel Milk Exosomes: An In Vitro Study.Veterinary sciences · 2023Article
- In vitro and in silico studies for the identification of anti-cancer and antibacterial peptides from camel milk protein hydrolysates.PloS one · 2023Article
- Protein Hydrolysates Derived from Animals and Plants-A Review of Production Methods and Antioxidant Activity.Foods (Basel, Switzerland) · 2022Review
- Novel Antioxidant Peptides fromFoods (Basel, Switzerland) · 2022Article
- Using RSM for Optimum of Optimum Production of Peptides from Edible Bird's Nest By-Product and Characterization of Its Antioxidant's Properties.Foods (Basel, Switzerland) · 2022Article
- Camel milk protectiveness toward multiple liver disorders: A review.Frontiers in nutrition · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peptides from natural sources such as milk are shown to have a wide spectrum of biological activities. In this study, three peptides with antioxidant capacity were identified from camel milk protein hydrolysate. Pepsin and pancreatin were used for hydrolysis of milk proteins. Ultrafiltration and reverse-phase high-performance liquid chromatography were used for the concentration and purification of the hydrolysate, respectively. Sequences of the three peptides, which were determined by matrix-assisted laser desorption/ionization time-of-flight spectrophotometry, were LEEQQQTEDEQQDQL [molecular weight (MW): 1860.85 Da, LL-15], YLEELHRLNAGY (MW: 1477.63 Da, YY-11), and RGLHPVPQ (MW: 903.04 Da, RQ-8). The 3-(4,5-dimethylthia-zol-2-yl)-2,5-diphenyltetrazolium bromide assay was used to evaluate the cytotoxicity of these chemically synthesized peptides against HepG2 cells. In vitro analysis showed antioxidant properties and radical scavenging activities of these peptides on 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)+, O
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