Evidence map›Paper›PMID 28911606›Full record

ReviewJournal of food and drug analysis2016

Inhibitory mechanism against oxidative stress of caffeic acid.

Farhan Ahmed Khan, Aneela Maalik, Ghulam Murtaza

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of food and drug analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it, 203 citations in OpenAlex.

  1. Pooled it
  2. Detoxifying Effects of a Phenolic-RichInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Polyphenol-enriched fraction ofFrontiers in pharmacology · 2026
    Article
  10. Review
  11. Article
  12. Article
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  14. Review
  15. Article
  16. Article
  17. Review
  18. Investigating the Health Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  19. Review
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Farhan Ahmed KhanDepartment of Chemistry, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
Aneela MaalikDepartment of Chemistry, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
Ghulam MurtazaDepartment of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
COMSATS University Islamabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this article is to summarize the reported antioxidant activities of a naturally abundant bioactive phenolic acid, caffeic acid (CA, 3,4-dihydroxycinnamic acid), so that new avenues for future research involving CA can be explored. CA is abundantly found in coffee, fruits, vegetables, oils, and tea. CA is among the most potential and abundantly found in nature, hydroxycinnamic acids with the potential of antioxidant behavior. Reactive oxygen species produced as a result of endogenous processes can lead to pathophysiological disturbances in the human body. Foods containing phenolic substances are a potential source for free radical scavenging; these chemicals are known as antioxidants. This review is focused on CA's structure, availability, and potential as an antioxidant along with its mode of action. A brief overview of the literature published about the prooxidant potential of caffeic acid as well as the future perspectives of caffeic acid research is described. CA can be effectively employed as a natural antioxidant in various food products such as oils.

Indexed as

Oxidative StressAntioxidantsCaffeic AcidsCoumaric AcidsHumansAntioxidantscaffeic acidCaffeic AcidsCoumaric Acidsanticancerantioxidanthydroxycinnamic acidprooxidantreactive oxygen species

Identifiers

PMID28911606
PMCPMC9337298
OpenAlexW2418702816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.