Evidence map›Paper›PMID 28911590›Full record

ArticleJournal of food and drug analysis2016

Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity.

Nelson Jeng-Yeou Chear, Kooi-Yeong Khaw, Vikneswaran Murugaiyah, Choon-Sheen Lai

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Free Radical Scavenging, Anti-Infectious, and Toxicity Activities fromAdvances in pharmacological and pharmaceutical sciences · 2022
    Article
  7. Review
  8. Article
  9. Frontiers in pharmacology · 2021
    Article
  10. Article
  11. Quantitative and Qualitative Characterization ofJournal of analytical methods in chemistry · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nelson Jeng-Yeou ChearCentre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia.
Kooi-Yeong KhawSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Vikneswaran MurugaiyahSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Choon-Sheen LaiCentre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia.
Universiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stenochlaena palustris fronds are popular as a vegetable in Southeast Asia. The objectives of this study were to evaluate the anticholinesterase properties and phytochemical profiles of the young and mature fronds of this plant. Both types of fronds were found to have selective inhibitory effect against butyrylcholinesterase compared with acetylcholinesterase. However, different sets of compounds were responsible for their activity. In young fronds, an antibutyrylcholinesterase effect was observed in the hexane extract, which was comprised of a variety of aliphatic hydrocarbons, fatty acids, and phytosterols. In the mature fronds, inhibitory activity was observed in the methanol extract, which contained a series of kaempferol glycosides. Our results provided novel information concerning the ability of S. palustris to inhibit cholinesterase and its phytochemical profile. Further research to investigate the potential use of this plant against Alzheimer's disease is warranted, however, young and mature fronds should be distinguished due to their phytochemical differences.

Indexed as

TracheophytaAcetylcholinesteraseAntioxidantsButyrylcholinesteraseCholinesterase InhibitorsGlycosidesInhibitory Concentration 50Plant ExtractsPlant LeavesAcetylcholinesteraseAntioxidantsButyrylcholinesteraseCholinesterase InhibitorsGlycosidesPlant ExtractsanticholinesteraseBlechnaceaefrond maturityphytochemical profileStenochlaena palustris

Identifiers

PMID28911590
PMCPMC9339560
OpenAlexW2294971711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.