Evidence map›Paper›PMID 28911189›Full record

ArticleEuropean heart journal2017

Long working hours as a risk factor for atrial fibrillation: a multi-cohort study.

Mika Kivimäki, Solja T Nyberg, G David Batty, Ichiro Kawachi, Markus Jokela, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr, Nico Dragano and 26 more

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 6 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 6 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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  17. The impact of long working hours on daily sodium intake.Annals of occupational and environmental medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 8 countries.

Mika KivimäkiDepartment of Epidemiology and Public Health, University College London, WC1E 6BT London, UK.
Solja T NybergClinicum, Faculty of Medicine, University of Helsinki, Tukholmankatu 8 B, 00290 Helsinki, Finland.
G David BattyDepartment of Epidemiology and Public Health, University College London, WC1E 6BT London, UK.
Ichiro KawachiDepartment of Social & Behavioral Sciences, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Kresge Building 7th Floor, Boston, Massachusetts 02115, USA.
Markus JokelaDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Haartmaninkatu 3, 00014 Helsinki, Finland.
Lars AlfredssonCentre for Occupational and Environmental Medicine, Stockholm County Council, Solnavägen 4, 113 65 Stockholm, Sweden.
Jakob B BjornerNational Research Centre for the Working Environment, Lersø Parkallé 105, 2100 Copenhagen ø, Denmark.
Marianne BorritzBispebjerg University Hospital Copenhagen, Department of Occupational and Environmental Medicine, Bispebjerg Bakke 23_20F, DK-2400 Copenhagen NV, Denmark.
Hermann BurrFederal Institute for Occupational Safety and Health (BAuA), Nöldnerstraße 40/42, 10317 Berlin, Germany.
Nico DraganoInstitute of Medical Sociology, Medical Faculty, University of Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Eleonor I FranssonSchool of Health and Welfare, Jönköping University, Barnarpsgatan 39, 551 11 Jönköping, Sweden.
Katriina HeikkiläDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, UK 15-17 Tavistock Place, WC1H 9SH London, UK.
Anders KnutssonDepartment of Health Sciences, Mid Sweden University, Holmgatan 10, 851 70 Sundsvall, Sweden.
Markku KoskenvuoClinicum, Faculty of Medicine, University of Helsinki, Tukholmankatu 8 B, 00290 Helsinki, Finland.
Meena KumariInstitute for Social and Economic Research, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, Essex, UK.
Ida E H MadsenNational Research Centre for the Working Environment, Lersø Parkallé 105, 2100 Copenhagen ø, Denmark.
Martin L NielsenAS3 Employment, AS3 Companies, Hasselager Centervej 35, DK-8260 VIBY J, Denmark.
Maria NordinStress Research Institute, Stockholm University, Frescati Hagväg 16 A, 114 19 Stockholm, Sweden.
Tuula OksanenFinnish Institute of Occupational Health, Topeliuksenkatu 41 B, 00250 Helsinki, Finland.
Jan H PejtersenDanish National Centre for Social Research, Herluf Trolles Gade 11, 1052 Copenhagen K, Denmark.
Jaana PenttiClinicum, Faculty of Medicine, University of Helsinki, Tukholmankatu 8 B, 00290 Helsinki, Finland.
Reiner RuguliesNational Research Centre for the Working Environment, Lersø Parkallé 105, 2100 Copenhagen ø, Denmark.
Paula SaloFinnish Institute of Occupational Health, Topeliuksenkatu 41 B, 00250 Helsinki, Finland.
Martin J ShipleyDepartment of Epidemiology and Public Health, University College London, WC1E 6BT London, UK.
Sakari SuominenUniversity of Skövde, Högskolevägen 28, 541 45 Skövde, Sweden.
Töres TheorellStress Research Institute, Stockholm University, Frescati Hagväg 16 A, 114 19 Stockholm, Sweden.
Jussi VahteraDepartment of Public Health, University of Turku, Joukahaisenkatu 3-5 A, 20520 Turku, Finland.
Peter WesterholmDepartment of Medical Sciences, Uppsala University, Akademiska sjukhuset, 75185 Uppsala, Sweden.
Hugo WesterlundStress Research Institute, Stockholm University, Frescati Hagväg 16 A, 114 19 Stockholm, Sweden.
Andrew SteptoeDepartment of Epidemiology and Public Health, University College London, WC1E 6BT London, UK.
Archana Singh-ManouxInserm U1018, Centre for Research in Epidemiology and Population Health, Hôpital Paul-Brousse 16 avenue Paul Vaillant-Couturier, Bâtiment 15/16, 94807 Villejuif Cedex, France.
Mark HamerSchool of Sport, Exercise and Health Sciences, National Centre Sport & Exercise Medicine, Loughborough University, Epinal Way, Loughborough LE11 3TU, UK.
Jane E FerrieSchool of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Marianna VirtanenFinnish Institute of Occupational Health, Topeliuksenkatu 41 B, 00250 Helsinki, Finland.
Adam G TabakDepartment of Epidemiology and Public Health, University College London, WC1E 6BT London, UK.
IPD-Work consortium
University of Helsinki · FINational Research Centre for the Working Environment · DKUniversity College London · GBUniversity of Turku · FIFinnish Institute of Occupational Health · FIStockholm University · SEBispebjerg Hospital · DKDanish National Centre for Social Research · DKFederal Institute for Occupational Safety and Health · DEHarvard University · USHeinrich Heine University Düsseldorf · DEHôpital Paul-Brousse · FRInstitute for Social and Economic Research · GBJönköping University · SEKarolinska Institutet · SELoughborough University · GBMid Sweden University · SESemmelweis University · HUThe Honourable Society of Lincoln's Inn · GBUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsStudies suggest that people who work long hours are at increased risk of stroke, but the association of long working hours with atrial fibrillation, the most common cardiac arrhythmia and a risk factor for stroke, is unknown. We examined the risk of atrial fibrillation in individuals working long hours (≥55 per week) and those working standard 35-40 h/week. METHODS AND

resultsIn this prospective multi-cohort study from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium, the study population was 85 494 working men and women (mean age 43.4 years) with no recorded atrial fibrillation. Working hours were assessed at study baseline (1991-2004). Mean follow-up for incident atrial fibrillation was 10 years and cases were defined using data on electrocardiograms, hospital records, drug reimbursement registers, and death certificates. We identified 1061 new cases of atrial fibrillation (10-year cumulative incidence 12.4 per 1000). After adjustment for age, sex and socioeconomic status, individuals working long hours had a 1.4-fold increased risk of atrial fibrillation compared with those working standard hours (hazard ratio = 1.42, 95% CI = 1.13-1.80, P = 0.003). There was no significant heterogeneity between the cohort-specific effect estimates (I2 = 0%, P = 0.66) and the finding remained after excluding participants with coronary heart disease or stroke at baseline or during the follow-up (N = 2006, hazard ratio = 1.36, 95% CI = 1.05-1.76, P = 0.0180). Adjustment for potential confounding factors, such as obesity, risky alcohol use and high blood pressure, had little impact on this association.

conclusionIndividuals who worked long hours were more likely to develop atrial fibrillation than those working standard hours.

Indexed as

AdolescentAdultAgedAtrial FibrillationCoronary DiseaseFemaleHumansHypertensionMaleMiddle AgedPrognosisProspective StudiesRisk FactorsStress, PsychologicalStrokeTime FactorsAtrial fibrillationCohort studyLife stressRisk factors

Identifiers

PMID28911189
PMCPMC5837794
OpenAlexW2636433405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.