Trial reportJournal of child and adolescent psychopharmacology2018
Quality of Life in Children and Youth with Obsessive-Compulsive Disorder.
Trial report in Journal of child and adolescent psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Defining Treatment Outcomes in Pediatric Obsessive-Compulsive Disorder Using a Self-Report Scale.Behavior therapy · 2019Trial
- Executive Functioning, Family Accommodation, and Treatment Response in Youth with OCD and Comorbid ADHD in a Partial Hospital Program.Child psychiatry and human development · 2026Article
- Mental health stigma in Latin American youth with obsessive-compulsive disorder.Psychiatry research · 2026Article
- Time-of-day differences in daily functioning in children with obsessive-compulsive disorder.Scientific reports · 2026Article
- Using latent patient-centered fear extinction profiles to guide treatment in pediatric OCD.Psychiatry research · 2025Article
- Potential for Harm in the Treatment of Pediatric Obsessive-Compulsive Disorder: Pitfalls and Best Practices.Research on child and adolescent psychopathology · 2025Review
- A mobile app to challenge obsessional beliefs in adolescents: a protocol of a two-armed, parallel randomized controlled trial.BMC psychiatry · 2024Article
- Predictors of health-related quality of life for children with neurodevelopmental conditions.Scientific reports · 2024Article
- Functional impairment in a Spanish Sample of Children and Adolescents with Obsessive-Compulsive Disorder.Child psychiatry and human development · 2024Article
- Parent-youth convergence (and divergence) in reports about pediatric quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Obsessive-compulsive disorder in youth and young adults with depression: Clinical characteristics of comorbid presentations.Journal of obsessive-compulsive and related disorders · 2023Article
- Secondary outcomes of enhanced cognitive behavioral therapy (eCBT) for children and adolescents with obsessive-compulsive disorder.Frontiers in human neuroscience · 2023Article
- Quality of life in pediatric patients with obsessive-compulsive disorder during and 3 years after stepped-care treatment.European child & adolescent psychiatry · 2022Article
- Irritability, Defiant and Obsessive-Compulsive Problems Development from Childhood to Adolescence.Journal of youth and adolescence · 2022Article
- Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder: 2021 Update.Focus (American Psychiatric Publishing) · 2021Article
- Developmental Considerations in Obsessive Compulsive Disorder: Comparing Pediatric and Adult-Onset Cases.Frontiers in psychiatry · 2021Review
- Temporal precedence of the change in obsessive-compulsive symptoms and change in depressive symptoms during exposure and response prevention for pediatric obsessive-compulsive disorders.Behaviour research and therapy · 2020Article
- Avoidance, Insight, Impairment Recognition Concordance, and Cognitive-Behavioral Therapy Outcomes in Pediatric Obsessive-Compulsive Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- Challenges in the diagnosis and treatment of pediatric obsessive-compulsive disorder.Indian journal of psychiatry · 2019Review
- Does higher severity really correlate with a worse quality of life in obsessive-compulsive disorder? A meta-regression.Neuropsychiatric disease and treatment · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study examined clinical correlates of quality of life (QoL), impact of treatment on QoL, and predictors of QoL change among children with obsessive-compulsive disorder (OCD).
methodsOne hundred forty-two children with primary OCD who were enrolled as part of a larger clinical trial participated. Children were administered a structured diagnostic interview, as well as clinician-administered measures of OCD and depression symptom severity. Children and parents completed reports of QoL, as well as measures of impairment and internalizing and externalizing symptoms. Youth received 10 sessions of family-based cognitive-behavioral therapy (CBT).
resultsAt baseline, QoL was inversely related to obsessive-compulsive symptom severity, impairment, externalizing and internalizing symptoms, and severity of depression symptoms according to children and parents. After CBT, QoL improved according to parent ratings, but not child ratings. None of the predictors examined were associated with changes in QoL scores over time. Impairment, and externalizing and internalizing symptoms predicted QoL after accounting for OCD symptom severity. After accounting for OCD symptoms, externalizing symptoms inversely predicted changes in QoL.
conclusionThese data suggest that QoL is related to more severe clinical presentation and improves with evidence-based treatment, but QoL improvements may be inversely related to externalizing symptomology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.