Evidence map›Paper›PMID 28906248›Full record

ArticleeLife2017

Transcription of a 5' extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter.

Minghao Chia, Amy Tresenrider, Jingxun Chen, Gianpiero Spedale, Victoria Jorgensen, Elçin Ünal, Folkert Jacobus van Werven

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 87 citations in OpenAlex.

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  9. Repression ofbioRxiv : the preprint server for biology · 2024
    Article
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  15. Article
  16. Article
  17. Article
  18. The Functional Meaning of 5'UTR in Protein-Coding Genes.International journal of molecular sciences · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Minghao ChiaThe Francis Crick Institute, London, United Kingdom.
Amy TresenriderDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Jingxun ChenDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Gianpiero SpedaleThe Francis Crick Institute, London, United Kingdom.
Victoria JorgensenDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Elçin ÜnalDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Folkert Jacobus van WervenThe Francis Crick Institute, London, United Kingdom.ORCID http://orcid.org/0000-0002-6685-2084
University of California, Berkeley · USThe Francis Crick Institute · GB

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
ILLUMINATING CELLULAR AGING PATHWAYS THROUGH GAMETOGENESISDP2AG055946 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2016 to 2016
$2.2M
Cancer Research UK 17576Cancer Research UK FC001203Medical Research Council FC001203NIA NIH HHS DP2 AG055946NIGMS NIH HHS T32 GM007232Wellcome Trust FC001203
6 · The paper itself

Abstract

Cell differentiation programs require dynamic regulation of gene expression. During meiotic prophase in

Indexed as

Gene Expression Regulation, FungalMeiosisTranscription, GeneticChromatinKinetochoresNuclear ProteinsPromoter Regions, GeneticRNA IsoformsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsChromatinNDC80 protein, S cerevisiaeNuclear ProteinsRNA IsoformsSaccharomyces cerevisiae ProteinschromatinchromosomesgenesinterferencemeiosismRNA isoformpromoterS. cerevisiaetranscription

Identifiers

PMID28906248
PMCPMC5655139
OpenAlexW2753956623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.