Evidence map›Paper›PMID 28906059›Full record

ReviewPhytochemical analysis : PCA2018

Benefits and Limitations of DNA Barcoding and Metabarcoding in Herbal Product Authentication.

Ancuta Cristina Raclariu, Michael Heinrich, Mihael Cristin Ichim, Hugo de Boer

Abstract readReview
In one paragraph

Review in Phytochemical analysis : PCA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Review
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  6. Pharmaceutics · 2026
    Review
  7. The complete chloroplast genome ofFrontiers in genetics · 2026
    Article
  8. KoreanFrontiers in pharmacology · 2026
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ancuta Cristina RaclariuNatural History Museum, University of Oslo, P.O. Box 1172, Blindern, 0318, Oslo, Norway.ORCID http://orcid.org/0000-0003-1860-9984
Michael HeinrichResearch Group of Pharmacognosy and Phytotherapy, Research Cluster 'Biodiversity and Medicines', UCL School of Pharmacy, University of London, 29-39 Brunswick Sq, London, WC1N 1AX, UK.
Mihael Cristin IchimStejarul Research Centre for Biological Sciences, National Institute of Research and Development for Biological Sciences, Alexandru cel Bun Street, 6, 610004, Piatra Neamt, Romania.
Hugo de BoerNatural History Museum, University of Oslo, P.O. Box 1172, Blindern, 0318, Oslo, Norway.ORCID http://orcid.org/0000-0003-1985-7859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHerbal medicines play an important role globally in the health care sector and in industrialised countries they are often considered as an alternative to mono-substance medicines. Current quality and authentication assessment methods rely mainly on morphology and analytical phytochemistry-based methods detailed in pharmacopoeias. Herbal products however are often highly processed with numerous ingredients, and even if these analytical methods are accurate for quality control of specific lead or marker compounds, they are of limited suitability for the authentication of biological ingredients.

objectiveTo review the benefits and limitations of DNA barcoding and metabarcoding in complementing current herbal product authentication.

methodRecent literature relating to DNA based authentication of medicinal plants, herbal medicines and products are summarised to provide a basic understanding of how DNA barcoding and metabarcoding can be applied to this field.

resultsDifferent methods of quality control and authentication have varying resolution and usefulness along the value chain of these products. DNA barcoding can be used for authenticating products based on single herbal ingredients and DNA metabarcoding for assessment of species diversity in processed products, and both methods should be used in combination with appropriate hyphenated chemical methods for quality control.

conclusionsDNA barcoding and metabarcoding have potential in the context of quality control of both well and poorly regulated supply systems. Standardisation of protocols for DNA barcoding and DNA sequence-based identification are necessary before DNA-based biological methods can be implemented as routine analytical approaches and approved by the competent authorities for use in regulated procedures. © 2017 The Authors. Phytochemical Analysis Published by John Wiley & Sons Ltd.

Indexed as

DNA Barcoding, TaxonomicEuropean UnionHerbal MedicineQuality ControlReference StandardsauthenticationDNA barcodingDNA metabarcodingherbal pharmacovigilanceherbal productsNMR metabolomicsqualitysafety

Identifiers

PMID28906059
PMCPMC5836936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.