Evidence map›Paper›PMID 28905887›Full record

ArticleGene therapy2017

An efficient, non-viral dendritic vector for gene delivery in tissue engineering.

D P Walsh, A Heise, F J O'Brien, S-A Cryan

Abstract read
PubMed Publisher
In one paragraph

Article in Gene therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

D P WalshSchool of Pharmacy, RCSI, Dublin, Ireland.
A HeiseCentre for Research in Medical Devices (CURAM), RCSI, Dublin and National University of Ireland, Galway, Ireland.
F J O'BrienTissue Engineering Research Group, Department of Anatomy, RCSI, Dublin, Ireland.
S-A CryanSchool of Pharmacy, RCSI, Dublin, Ireland.
Ollscoil na Gaillimhe – University of Galway · IERoyal College of Surgeons in Ireland · IETrinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent developments within the field of tissue engineering (TE) have shown that biomaterial scaffold systems can be augmented via the incorporation of gene therapeutics. The objective of this study was to assess the potential of the activated polyamidoamine dendrimer (dPAMAM) transfection reagent (Superfect

Indexed as

AnimalsBiocompatible MaterialsCollagenDendrimersDendritesDurapatiteGenetic TherapyGene Transfer TechniquesMesenchymal Stem CellsPlasmidsPolyethyleneimineRatsRats, Sprague-DawleyTissue EngineeringTissue ScaffoldsTransfectionBiocompatible MaterialsCollagenDendrimersDurapatitenano-hydroxyapatite-collagenPAMAM StarburstPolyethyleneimine

Identifiers

PMID28905887
OpenAlexW2736781640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.