Evidence map›Paper›PMID 28905820›Full record

ReviewIndian journal of ophthalmology2017

Recent advances in corneal collagen cross-linking.

Gitansha Shreyas Sachdev, Mahipal Sachdev

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Visual rehabilitation in keratoconus by altering corneal shape using the corneal crosslinking pen: initial results.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Trial
  2. Article
  3. Article
  4. Outcomes of localized corneal collagen crosslinking with a conventional device in progressive keratoconus.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  5. Review
  6. Severe Complications after Corneal Collagen Cross-Linking (CXL).Klinische Monatsblatter fur Augenheilkunde · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Biomechanical Impact of Localized Corneal Cross-linking Beyond the Irradiated Treatment Area.Journal of refractive surgery (Thorofare, N.J. : 1995) · 2019
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gitansha Shreyas SachdevDr. Gitansha Shreyas Sachdev, The Eye Foundation, Coimbatore, India.
Mahipal SachdevCentre for Sight, New Delhi, India.
Centre for Sight · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide implications in the form of accelerated and pulsed protocols. Newer advancements in technology include various riboflavin formulations and the ability to deliver higher fluence protocols with customised irradiation patterns. A greater degree of customisation is likely the path forward, which will aim at achieving refractive improvements along with disease stability. The use of cross-linking for myopic correction is another avenue under exploration. Combination of half fluence cross-linking with refractive correction for high errors to prevent post LASIK regression is gaining interest. This review aims to highlight the various advancements in the cross-linking technology and its clinical applications.

Indexed as

CollagenCorneaCorneal TopographyCross-Linking ReagentsHumansKeratoconusPhotochemotherapyPhotosensitizing AgentsCollagenCross-Linking ReagentsPhotosensitizing Agents

Identifiers

PMID28905820
PMCPMC5621259
OpenAlexW2755758963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.