ArticleSICOT-J2017
Giant cell tumor of bone revisited.
Article in SICOT-J, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Management of giant cell tumors of the distal radius: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Pooled it
- [Differential diagnoses of malignant bone marrow diseases].Radiologie (Heidelberg, Germany) · 2026Review
- A Rare Case of Giant Cell tumor of Bone in Distal Tibia.Journal of orthopaedic case reports · 2026Article
- Secondary Malignant Transformation of Giant Cell Tumor of Bone Nine Years After Initial Curettage: A Case Report and Literature Review.Reports (MDPI) · 2026Article
- Dual-target neoadjuvant therapy with denosumab and sunitinib for giant cell tumor of bone: a sarcoma center experience.Journal of bone oncology · 2026Article
- Functional Outcome and Complications of Wide Excision of the Distal End of Radius and Reconstruction with Ulnar Transposition in Campanacci Grade III Giant Cell Tumor: A Longitudinal Study of 14 Cases in South India.Journal of orthopaedic case reports · 2026Article
- Dual-energy CT fusion imaging improves ice-ball visualization in bone during spinal cryoablation in porcine cadavers.European radiology experimental · 2026Article
- A Novel Approach to Proximal Humerus Giant Cell Tumor: Cement Spacer and Screw Interdigitation for Optimal Stability.Journal of orthopaedic case reports · 2026Article
- Freezing nitrogen ethanol composite as an alternative to liquid nitrogen in giant cell tumor cryotherapy: a case report and literature review.International journal of surgery case reports · 2026Article
- Establishment and characterization of NCC-GCTB16-C1: novel patient-derived cell line of giant cell tumor of bone.Human cell · 2026Article
- Giant Cell Tumor of Bone: Biology, Pathophysiology, and Histopathology in the Era of H3F3A.Biomedicines · 2026Review
- Giant Cell Tumor of the Olecranon With a Displaced Pathological Fracture Successfully Treated by Intralesional Curettage and Plate Fixation: A Case Report.Case reports in orthopedics · 2026Article
- Patterns and Timing of Local Recurrence in Benign Bone Tumors.The Iowa orthopaedic journal · 2026Article
- Soft tissue recurrence in giant cell tumor of Bone: A comprehensive review of pathogenesis, imaging features, and clinical management.Journal of bone oncology · 2025Review
- Clinical Audit of Denosumab Biosimilar for Aggressive GCT of Bone: A Tertiary Care Center Retrospective Analysis.South Asian journal of cancer · 2025Article
- A Rare Case Report of Advanced Surgical Management of Proximal Tibia Giant Cell Tumor in a 20-year-old Girl-Extended Curettage and Sandwich Technique.Journal of orthopaedic case reports · 2025Article
- A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Article
- An unusual case of multiple primary tumours involving the long bone and oral cavity.Oral and maxillofacial surgery · 2025Article
- Efficacy of Arthroscopic Surgery in the Management of Synovial Giant Cell Tumors: a Case Report.Maedica · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Giant cell tumor (GCT) of bone is a locally aggressive benign neoplasm that is associated with a large biological spectrum ranging from latent benign to highly recurrent and occasionally metastatic malignant bone tumor. It accounts for 4-10% of all bone tumors and typically affects the meta-epiphyseal region of long bones of young adults. The most common site involved is the distal femur, followed by the distal radius, sacrum, and proximal humerus. Clinical symptoms are nonspecific and may include local pain, swelling, and limited range of motion of the adjacent joint. Radiographs and contrast-enhanced magnetic resonance imaging (MRI) are the imaging modalities of choice for diagnosis. Surgical treatment with curettage is the optimal treatment for local tumor control. A favorable clinical outcome is expected when the tumor is excised to tumor-free margins, however, for periarticular lesions this is usually accompanied with a suboptimal functional outcome. Local adjuvants have been used for improved curettage, in addition to systematic agents such as denosumab, bisphosphonates, or interferon alpha. This article aims to discuss the clinicopathological features, diagnosis, and treatments for GCT of bone.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.