ReviewTuberculosis and respiratory diseases2017
The Relationship between Airway Inflammation and Exacerbation in Chronic Obstructive Pulmonary Disease.
Review in Tuberculosis and respiratory diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Circulating Levels of Hydrogen Sulfide (HBiomolecules · 2023Pooled it
- The role of air pollution (PM and NOEnvironmental research · 2020Pooled it
- Sarcopenia and Frailty in COPD: Mechanisms, Relationship with Malnutrition and Potential Therapeutic Interventions.Nutrients · 2026Review
- The Role of Tyrosine and C-Reactive Protein in COPD Exacerbations.Journal of clinical medicine · 2025Article
- Chronic Diseases and Influenza Vaccines.Vaccines · 2025Review
- Effect of plasma free fatty acids on lung function in male COPD patients.Scientific reports · 2025Article
- Construction and validation of a prediction model for developing type 2 diabetes mellitus in patients with chronic obstructive pulmonary disease.Frontiers in endocrinology · 2025Article
- Immune mediators in heart-lung communication.Pflugers Archiv : European journal of physiology · 2025Review
- Inflammation as the nexus: exploring the link between acute myocardial infarction and chronic obstructive pulmonary disease.Frontiers in cardiovascular medicine · 2024Review
- Takotsubo syndrome and respiratory diseases: a systematic review.European heart journal open · 2022Review
- Assessment of Inter-relationship between Anemia and COPD In Accordance with Altitude.The open respiratory medicine journal · 2022Article
- Gallic acid ameliorates COPD-associated exacerbation in mice.Molecular and cellular biochemistry · 2021Article
- Observational
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) is associated with abnormal inflammatory response and airflow limitation. Acute exacerbation involves increased inflammatory burden leading to worsening respiratory symptoms, including dyspnea and sputum production. Some COPD patients have frequent exacerbations (two or more exacerbations per year). A substantial proportion of COPD patients may remain stable without exacerbation. Bacterial and viral infections are the most common causative factors that breach airway stability and lead to exacerbation. The increasing prevalence of exacerbation is associated with deteriorating lung function, hospitalization, and risk of death. In this review, we summarize the mechanisms of airway inflammation in COPD and discuss how bacterial or viral infection, temperature, air pollution, eosinophilic inflammation, and concomitant chronic diseases increase airway inflammation and the risk of exacerbation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.