Evidence map›Paper›PMID 28905162›Full record

Observational studyInternational journal of clinical pharmacy2017

Quality of prescribing in community-dwelling elderly patients in France: an observational study in community pharmacies.

E Bourcier, F Mille, V Brunie, V Korb-Savoldelli, C Lafortune, M Buyse, C Fernandez, P Hindlet

Abstract readObservational Study
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In one paragraph

Observational study in International journal of clinical pharmacy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

E BourcierFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France. elsa.bourcier@aphp.fr.ORCID http://orcid.org/0000-0003-4605-4963
F MilleService de Pharmacie, Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, 184, rue du Faubourg Saint Antoine, 75012, Paris, France.
V BrunieFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.
V Korb-SavoldelliFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.
C LafortuneFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.
M BuyseFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.
C FernandezFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.
P HindletFaculté de Pharmacie, Université Paris-Sud, 5, rue Jean-Baptiste Clément, 92296, Chatenay-Malabry, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In order to ensure safer prescriptions in the elderly, lists of potentially inappropriate medications (PIMs) and guidelines have been introduced. Whereas the effectiveness of these measures has been well studied in hospitals, data are sparse for the community-dwelling patients. Objective To assess the quality of prescriptions among community-dwelling elderly patients, and potential associations between prescription patterns, patient characteristics and medication adherence. Setting Community pharmacies in France. Method We conducted a prospective observational study between January and June 2013. Patients aged 75 and over coming to the community pharmacy with a prescription from a general practitioner were invited to participate to the study. The compliance of the prescription was assessed with regards to Beers Criteria and French Health Authority guidelines (FHA) for prescription in the elderly, the degree of adherence was assessed with the Girerd score. Main outcome measure Percentage of prescriptions compliant with Beers Criteria and FHA guidelines. Results Among the 1206 prescriptions analysed, 67.49% (n = 814) contained a PIM. Only 12.77% (n = 154) complied with mandatory requirements of the FHA. Prescriptions were ordered by therapeutic field in 51.24% (n = 618) of cases. Dosing regimen was incomplete in 57.21% (n = 690) of prescriptions. Only 29.19% (n = 352) of patients reported no difficulty with regard to adherence (Girerd score = 0). The use of International Non-proprietary Name was associated with an increased risk of nonadherence (adjusted OR = 1.59 [95% CI = 1.13-2.23] and 1.68 [95% CI = 1.12-2.49] respectively). Patient satisfaction with formulation was associated with a lower risk of non-adherence (adjusted OR = 0.63 [95% CI = 0.45-0.90]). Conclusion A substantial proportion of patients are exposed to PIMs and prescriptions that do not comply with the FHA Guidelines. This issue, as well as identified risk factors for non-adherence, should be taken into consideration by general practitioners and community pharmacists when prescribing/dispensing medications to the elderly.

Indexed as

Drug MonitoringAgedAged, 80 and overCommunity Pharmacy ServicesFemaleFranceGuideline AdherenceHumansInappropriate PrescribingIndependent LivingMalePatient SatisfactionPotentially Inappropriate Medication ListProspective StudiesAgedCommunity pharmacyDrug utilization reviewFranceMedication adherencePotentially inappropriate medication

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.