ReviewBioMed research international2017
Diabetic Foot Ulcers and Epidermal Growth Factor: Revisiting the Local Delivery Route for a Successful Outcome.
Open access · hybridAbstract readReview
In one paragraph
Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Epidermal Growth Factor is Effective in the Treatment of Diabetic Foot Ulcers: Meta-Analysis and Systematic Review.International journal of environmental research and public health · 2019Pooled it
- The appropriate management algorithm for diabetic foot: A single-center retrospective study over 12 years.Medicine · 2018Trial
- Intralesional Epidermal Growth Factor and Its Association with Reamputation and Level-Up Amputation in Diabetic Foot Patients with Post-Amputation Flap Necrosis: Clinical Outcomes and Macrophage Dynamics.Medicina (Kaunas, Lithuania) · 2026Observational
- Angiogenin alleviates lipotoxicity-induced impairment of skin wound healing.Cellular & molecular biology letters · 2026Article
- The In Vitro Wound-Scratch Assay: Applications, Technical Advances, and Limitations in Wound Healing Research.International wound journal · 2026Review
- SOX2-Dependent Wound Repair Signature Triggers Prohealing Outcome in Hyperglycemic Wounds.The Journal of investigative dermatology · 2025Article
- "An Effective Solution to Accelerate the Healing of Complex Ulcers Using Recombinant Human Epidermal Growth Factor (Intralesional Application): A Review".Drug design, development and therapy · 2025Review
- Innovative Nanocomposites for Drug Delivery: A Novel Approach for Diabetic Foot Ulcer.Current drug delivery · 2025Review
- Epidermal Growth Factor Intralesional Delivery in Chronic Wounds: The Pioneer and Standalone Technique for Reversing Wound Chronicity and Promoting Sustainable Healing.International journal of molecular sciences · 2024Review
- Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing.Tissue engineering and regenerative medicine · 2024Article
- Review
- Development of a Wound-Healing Protocol for In Vitro Evaluation of Urothelial Cell Growth.Methods and protocols · 2023Article
- EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies.Archives of pharmacal research · 2023Review
- Stem Cell's Secretome Delivery Systems.Advanced pharmaceutical bulletin · 2023Review
- Effects of microRNAs on angiogenesis in diabetic wounds.Frontiers in medicine · 2023Review
- Efficacy Comparison Study of Human Epidermal Growth Factor (EGF) between Heberprot-PGeriatrics (Basel, Switzerland) · 2022Article
- From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy.International journal of molecular sciences · 2021Article
- Diabetic Wound-Healing Science.Medicina (Kaunas, Lithuania) · 2021Review
- Film-Forming Spray of Water-Soluble Chitosan Containing Liposome-Coated Human Epidermal Growth Factor for Wound Healing.Molecules (Basel, Switzerland) · 2021Article
- Growth Factors, Reactive Oxygen Species, and Metformin-Promoters of the Wound Healing Process in Burns?International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 2 countries.
Jorge Berlanga-AcostaWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.ORCID 0000-0001-9797-1986
José Fernández-MontequínNational Institute of Angiology and Vascular Surgery, Calzada del Cerro No. 1551, El Cerro, Havana, Cuba.
Calixto Valdés-PérezNational Institute of Angiology and Vascular Surgery, Calzada del Cerro No. 1551, El Cerro, Havana, Cuba.
William Savigne-GutiérrezNational Institute of Angiology and Vascular Surgery, Calzada del Cerro No. 1551, El Cerro, Havana, Cuba.
Yssel Mendoza-MaríWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.ORCID 0000-0002-2788-0701
Ariana García-OjalvoWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Viviana Falcón-CamaWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Diana García Del Barco-HerreraWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Maday Fernández-MayolaWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Héctor Pérez-SaadWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Eulogio Pimentel-VázquezWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Aleida Urquiza-RodríguezDermatology Department, Center for Surgical and Medical Research, Calle 216 y 11-B, Reparto Siboney, Playa, Havana, Cuba.
Moshe KulikovskyLin Medical Center, Rehov Vardia 12, 3465712 Haifa, Israel.
Gerardo Guillén-NietoWound Healing and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Ave 31 e/158 and 190, Cubanacan, Playa, P.O. Box 10600, Havana, Cuba.
Centro de Ingeniería Genética y Biotecnología · CUCenter of Molecular Immunology (Cuba) · CUHaifa Medical Center · IL
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soon after epidermal growth factor (EGF) discovery, some
Indexed as
Administration, TopicalCellular MicroenvironmentDiabetic FootEpidermal Growth FactorHumansReceptor Protein-Tyrosine KinasesWound HealingEpidermal Growth FactorReceptor Protein-Tyrosine Kinases
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.