ReviewBioMed research international2017
Sodium Hypochlorite Irrigation and Its Effect on Bond Strength to Dentin.
Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Effect of collagen crosslinkers on sodium hypochlorite treated dentin bond strength: a systematic review and meta-analysis.Frontiers in bioengineering and biotechnology · 2025Pooled it
- Which Zirconia Surface-cleaning Strategy Improves Adhesion of Resin Composite Cement after Saliva Contamination? A Systematic Review and Meta-Analysis.The journal of adhesive dentistry · 2022Pooled it
- Normal Saline or Sodium Hypochlorite Irrigation for Vital Pulp Therapy? A Non-Inferiority Randomized Controlled Trial.European endodontic journal · 2024Trial
- The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial.Clinical oral investigations · 2024Trial
- Influence of Different Cavity Disinfection Protocols on Adhesion at the Resin Composite-Dentin Interface.Polymers · 2026Article
- Article
- Shear bond strength analysis of self-etch and total-etch adhesive systems on antioxidant-treated dentin in post-endodontic restoration.Frontiers in dental medicine · 2026Article
- Comparative evaluation ofBiomaterial investigations in dentistry · 2026Article
- Does cleaning of post space before cementation of fiber reinforced post affect the push-out bond strength to resin cement?BMC oral health · 2025Article
- Impact of sodium hypochlorite on the dissolution of soft tissue with photon-initiated photoacoustic streaming (PIPS) activation.BMC oral health · 2025Article
- Role of root canal sealers and dentin surface pretreatment on pull-out strength of customized resilient ceramic posts-and-cores.BMC oral health · 2025Article
- Advancing Adhesive Strategies for Endodontically Treated Teeth-Part II: Dentin Sealing Before Irrigation Increases Long-Term Microtensile Bond Strength to Coronal Dentin.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Article
- Advancing Adhesive Strategies for Endodontically Treated Teeth-Part I: Impact of Endodontic Irrigation Protocols on the Chemical Composition and Structural Integrity of Coronal Dentin.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Article
- Management of Enterococcus faecalis associated endodontic infection using gold nanogel: An in-vitro study.The Saudi dental journal · 2025Article
- SWEEPS-Assisted Antibacterial Photodynamic Therapy Against Dual-Species Biofilms in Mandibular Molars: An In Vitro Study.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Tooth and Composite Discoloration After Photodynamic Therapy with Different Photosensitizers and Cleansers Under Accelerated Aging Conditions.Journal of lasers in medical sciences · 2025Article
- A comparison of four decontamination procedures in Reusing healing abutments: An in vitro study.The Saudi dental journal · 2024Article
- Cytotoxic Effect of Two Different Concentrations of Sodium Hypochlorite: An In-Vitro Study.Cureus · 2024Article
- Article
- Antimicrobial activity of laser assisted endodontic therapy in disinfecting root canals.Bioinformation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective shaping and cleaning of root canals are essential for the success of endodontic treatment. Due to the complex anatomy of root canal spaces, the use of various instrumentation techniques alone is not effective in producing bacteria-free root canal spaces. Irrigation, disinfectants, rinses, and intervisit medications are used in conjunction with the mechanical instrumentation to ensure the success of endodontic treatment. Sodium hypochlorite (NaOCl), a halogenated compound, is routinely used to irrigate the root canal during endodontic treatments. NaOCl has been known for its antibacterial action, proteolytic and dissolution capacity, and debridement properties. NaOCl, however, can alter the composition of dentin and hence its interaction with the adhesive resins used to bond the restorative materials to treated dentin. This review therefore covers in depth the action of NaOCl on dentin-adhesive resin bond strength including both enhancement and reduction, then mechanisms proposed for such action, and finally how the adverse action of NaOCl on dentin can be reversed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.