Evidence map›Paper›PMID 28904656›Full record

ArticleThe Pan African medical journal2017

Reversal of tenofovir induced nephrotoxicity: case reports of two patients.

Fatuma Some, Mathew Koech, Emily Chesire, Gabriel Kigen

Abstract readCase Reports
In one paragraph

Article in The Pan African medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatuma SomeDepartment of Medicine, Moi University School of Medicine, P.O. Box 4606, Eldoret, Kenya.
Mathew KoechDepartment of Medicine, Moi University School of Medicine, P.O. Box 4606, Eldoret, Kenya.
Emily ChesireMoi Teaching and Referral Hospital, P.O. Box 3, Eldoret, Kenya.
Gabriel KigenDepartment of Pharmacology and Toxicology, Moi University School of Medicine, P.O. Box 4606, Eldoret, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of the antiretroviral drug tenofovir has been associated with nephrotoxicity. However, the overall impact of this adverse effect has not comprehensively evaluated. Some researchers have reported that it is quite severe to warrant monitoring for renal toxicity, while others have concluded that the magnitude may not be that significant. We report two clinical cases seen in our renal clinic with high creatinine levels suggestive of nephrotoxicity who reverted back to normality upon withdrawal of tenofovir.

Indexed as

Anti-HIV AgentsCreatinineHumansKidney DiseasesMaleMiddle AgedTenofovirAnti-HIV AgentsCreatinineTenofovirCase reportHIV/AIDsnephrotoxicityreversaltenofovir

Identifiers

PMID28904656
PMCPMC5567942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.