ReviewEvidence-based complementary and alternative medicine : eCAM2017
Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence.
Review in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Pooled it
- Herbal Remedies for Skin Diseases in Serbian Folk Medicine: A Review of 19th- and 20th-Century Practices.Plants (Basel, Switzerland) · 2026Review
- Protective effect ofToxicon: X · 2026Article
- Enhancing Venom Lethality: The Incompatibility ofArchives of Razi Institute · 2025Article
- A Review of the Main Biologically Active Compounds of the GenusPharmaceuticals (Basel, Switzerland) · 2025Review
- Anti-alkaline phosphatases (ALP) potentials of potent 4-aminobenzenesulfonamide derivatives againstFuture medicinal chemistry · 2025Article
- Ethnobotanical study of traditional antivenom treatments in Burkina Faso.Tropical medicine and health · 2025Article
- Exploiting exopolysaccharides from microalgae to block the toxic in vitro effects of Bothrops sp. venom.Scientific reports · 2025Article
- Article
- A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment.Frontiers in pharmacology · 2025Review
- Ethnomedicinal breakthroughs in snake bite therapy: From folklore to forefront.Toxicology reports · 2024Review
- Indian Medicinal Plant-Derived Phytochemicals as Potential Antidotes for Snakebite: A Pharmacoinformatic Study of Atrolysin Inhibitors.International journal of molecular sciences · 2024Article
- Three finger toxins of elapids: structure, function, clinical applications and its inhibitors.Molecular diversity · 2024Review
- Therapeutic itineraries of snakebite victims and antivenom access in southern Mexico.PLoS neglected tropical diseases · 2024Article
- Pharmacological Significance ofFoods (Basel, Switzerland) · 2024Review
- Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.Communications biology · 2024Review
- Preserving Ethnoveterinary Medicine (EVM) along the Transhumance Routes in Southwestern Angola: Synergies between International Cooperation and Academic Research.Plants (Basel, Switzerland) · 2024Article
- Evaluation of Neutralization Potential ofIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Community members and healthcare workers' priorities for the control and prevention of snakebite envenoming in Ghana.PLoS neglected tropical diseases · 2023Article
- A First Look at the Inhibitory Potential ofToxins · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects. Thus, the search for complementary alternatives for snakebite treatment is relevant. There are several reports of the popular use of medicinal plants against snakebites worldwide. In recent years, many studies have been published giving pharmacological evidence of benefits of several vegetal species against local effects induced by a broad range of snake venoms, including inhibitory potential against hyaluronidase, phospholipase, proteolytic, hemorrhagic, myotoxic, and edematogenic activities. In this context, this review aimed to provide an updated overview of medicinal plants used popularly as antiophidic agents and discuss the main species with pharmacological studies supporting the uses, with emphasis on plants inhibiting local effects of snake envenomation. The present review provides an updated scenario and insights into future research aiming at validation of medicinal plants as antiophidic agents and strengthens the potentiality of ethnopharmacology as a tool for design of potent inhibitors and/or development of herbal medicines against venom toxins, especially local tissue damage.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.