ArticleScientific reports2017
Response dynamics of rat barrel cortex neurons to repeated sensory stimulation.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- A versatile platform for two-photon neuronal population voltage imaging across cortical depths.Nature methods · 2026Article
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- Sensory adaptation supports flexible evidence accumulation during perceptual decision making.bioRxiv : the preprint server for biology · 2026Article
- Correlation of zero echo time functional MRI with neuronal activity in rats.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Article
- Multiple Distinct Timescales of Rapid Sensory Adaption in the Thalamocortical Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- MULTIPLE DISTINCT TIMESCALES OF RAPID SENSORY ADAPATION IN THE THALAMOCORTICAL CIRCUIT.bioRxiv : the preprint server for biology · 2024Article
- Adapting and facilitating responses in mouse somatosensory cortex are dynamic and shaped by experience.Current biology : CB · 2024Article
- Cerebrospinal fluid solute transport associated with sensorimotor brain activity in rodents.Scientific reports · 2023Article
- PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury.Experimental neurology · 2023Article
- Vitamin C-reduced graphene oxide improves the performance and stability of multimodal neural microelectrodes.iScience · 2022Article
- A novel stimulator to investigate the tuning of multi-whisker responsive neurons for speed and the direction of global motion: Contact-sensitive moving stimulator for multi-whisker stimulation.Journal of neuroscience methods · 2022Article
- Rapid Cortical Adaptation and the Role of Thalamic Synchrony during Wakefulness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- A protocol for simultaneousSTAR protocols · 2021Article
- Cross-Whisker Adaptation of Neurons in Layer 2/3 of the Rat Barrel Cortex.Frontiers in systems neuroscience · 2021Article
- Sensory Adaptation in the Whisker-Mediated Tactile System: Physiology, Theory, and Function.Frontiers in neuroscience · 2021Review
- Multiple Timescales Account for Adaptive Responses across Sensory Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
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Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuronal adaptation is a common feature observed at various stages of sensory processing. Here, we quantified the time course of adaptation in rat somatosensory cortex. Under urethane anesthesia, we juxta-cellularly recorded single neurons (n = 147) while applying a series of whisker deflections at various frequencies (2-32 Hz). For ~90% of neurons, the response per unit of time decreased with frequency. The degree of adaptation increased along the train of deflections and was strongest at the highest frequency. However, a subset of neurons showed facilitation producing higher responses to subsequent deflections. The response latency to consecutive deflections increased both for neurons that exhibited adaptation and for those that exhibited response facilitation. Histological reconstruction of neurons (n = 45) did not reveal a systematic relationship between adaptation profiles and cell types. In addition to the periodic stimuli, we applied a temporally irregular train of deflections with a mean frequency of 8 Hz. For 70% of neurons, the response to the irregular stimulus was greater than that of the 8 Hz regular. This increased response to irregular stimulation was positively correlated with the degree of adaptation. Altogether, our findings demonstrate high levels of diversity among cortical neurons, with a proportion of neurons showing facilitation at specific temporal intervals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.