Noninvasive high-frequency ventilation and the errors from the past: designing simple trials neglecting complex respiratory physiology.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

1. Evidence certainty in neonatology-a meta-epidemiological analysis of Cochrane reviews.European journal of pediatrics · 2025
   Pooled it
2. Non-invasive high-frequency ventilation in newborn infants with respiratory distress.The Cochrane database of systematic reviews · 2024
   Pooled it
3. Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials.Respiratory research · 2019
   Pooled it
4. Non-invasive high-frequency oscillation ventilation versus nasal CPAP as primary respiratory support in preterm neonates ≥ 30 weeks with RDS: a non-inferiority randomized controlled trial.European journal of pediatrics · 2026
   Trial
5. The effect of NHFOV on hemodynamics in mild and moderately preterm neonates: a randomized clinical trial.European journal of pediatrics · 2024
   Trial
6. Effectiveness of Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation vs Noninvasive High-Frequency Oscillatory Ventilation as Support After Extubation of Neonates Born Extremely Preterm or With More Severe Respiratory Failure: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2023
   Trial
7. Point-of-care lung ultrasound in neonatology: classification into descriptive and functional applications.Pediatric research · 2021
   Review
8. Continuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial.BMC pediatrics · 2019
   Article

Corrections and comments

• Commented on by
  Response to 'Non-invasive high frequency ventilation and the errors from the past: designing simple trials neglecting complex respiratory physiology'.2017
• Comment on
  Non-invasive high-frequency ventilation versus bi-phasic continuous positive airway pressure (BP-CPAP) following CPAP failure in infants <1250 g: a pilot randomized controlled trial.2017

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as