Evidence map›Paper›PMID 28904402›Full record

ArticleScientific reports2017

Power frequency magnetic field promotes a more malignant phenotype in neuroblastoma cells via redox-related mechanisms.

S Falone, S Santini, V Cordone, P Cesare, A Bonfigli, M Grannonico, G Di Emidio, C Tatone, M Cacchio, F Amicarelli

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. The impact of mitochondria on cancer treatment resistance.Cellular oncology (Dordrecht, Netherlands) · 2021
    Review
  10. Mitochondrial Sirtuins in Reproduction.Antioxidants (Basel, Switzerland) · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Significant Cellular Viability Dependence on Time Exposition at ELF-EMF and RF-EMF In Vitro Studies.International journal of environmental research and public health · 2019
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

S FaloneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy. stefano.falone@univaq.it.ORCID 0000-0002-5978-0545
S SantiniDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.ORCID 0000-0001-6577-5892
V CordoneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.ORCID 0000-0003-2791-8121
P CesareDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
A BonfigliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
M GrannonicoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
G Di EmidioDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
C TatoneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
M CacchioDepartment of Neurosciences, Imaging and Clinical Sciences, University "G. d'Annunzio", Chieti Scalo (CH), Italy.
F AmicarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
University of L'Aquila · ITUniversity of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In accordance with the classification of the International Agency for Research on Cancer, extremely low frequency magnetic fields (ELF-MF) are suspected to promote malignant progression by providing survival advantage to cancer cells through the activation of critical cytoprotective pathways. Among these, the major antioxidative and detoxification defence systems might be targeted by ELF-MF by conferring cells significant resistance against clinically-relevant cytotoxic agents. We investigated whether the hyperproliferation that is induced in SH-SY5Y human neuroblastoma cells by a 50 Hz, 1 mT ELF magnetic field was supported by improved defence towards reactive oxygen species (ROS) and xenobiotics, as well as by reduced vulnerability against both H

Indexed as

Magnetic FieldsOxidation-ReductionBiomarkersCell Line, TumorDoxorubicinHumansHydrogen PeroxideInactivation, MetabolicNeoplasm GradingNeuroblastomaNF-E2-Related Factor 2Oxidative StressReactive Oxygen SpeciesSirtuin 1Sirtuin 3BiomarkersDoxorubicinHydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2Reactive Oxygen SpeciesSIRT1 protein, humanSIRT3 protein, humanSirtuin 1Sirtuin 3

Identifiers

PMID28904402
PMCPMC5597619
OpenAlexW2751977284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.