Evidence map›Paper›PMID 28904361›Full record

SynthesisScientific reports2017

Intrafascial versus interfascial nerve sparing in radical prostatectomy for localized prostate cancer: a systematic review and meta-analysis.

Hong Weng, Xian-Tao Zeng, Sheng Li, Xiang-Yu Meng, Ming-Jun Shi, Da-Lin He, Xing-Huan Wang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  15. Neurovascular bundle preservation in robotic-assisted radical prostatectomy: How I do it after 15.000 cases.International braz j urol : official journal of the Brazilian Society of Urology
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hong WengDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xian-Tao ZengDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Sheng LiCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xiang-Yu MengCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Ming-Jun ShiInstitut Curie, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche 144, Paris, 75248, France.
Da-Lin HeDepartment of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Xing-Huan WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. wangxinghuan1965@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to systematically evaluate the effectiveness and safety of the intrafascial and interfascial nerve sparing (ITR-NS and ITE-NS) radical prostatectomy. PubMed, Embase, and Cochrane Library databases were searched for eligible studies. Meta-analysis with random-effects model was performed. Six comparative trials were selected and embraced in this research, including one randomized controlled trial, three prospective comparative trials, and two retrospective comparative trials. With regard to perioperative parameters, no significant association of operative time, blood loss, transfusion rates, duration of catheterization, and hospital stay existed between ITR-NS and ITE-NS. With respect to the functional results, ITR-NS had advantages in terms of both continence and potency recovery compared with ITE-NS. In reference to the oncologic results, the ITR-NS showed lower overall positive surgical margin (PSM) compared with ITE-NS but pT2 PSM and biochemical recurrence free rates were similar to the two surgical types. This study demonstrates that ITR-NS has better continence at 6 mo and 36 mo and better potency recovery at 6 mo and 12 mo postoperatively, regardless of the surgical technique. The cancer control of ITR-NS was also better than that of ITE-NS. This may be explained by the fact that patients in ITE-NS group present higher risk cancer than patients in ITR-NS group.

Indexed as

Organ Sparing TreatmentsFasciaHumansMaleNeoplasm StagingOdds RatioProstatectomyProstatic NeoplasmsPublication BiasTreatment Outcome

Identifiers

PMID28904361
PMCPMC5597634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.