ArticleScientific reports2017
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 84 citations in OpenAlex.
- Immune responses associated with protection induced by chemoattenuated PfSPZ vaccine in malaria-naive Europeans.JCI insight · 2024Trial
- Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial.Nature medicine · 2021Trial
- Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults.Malaria journal · 2019Trial
- Cellular and molecular interactions underlying the peripheral immune responses to blood-stage malaria infections.ImmunoHorizons · 2026Review
- Cytotoxic Vδ2+ T cell subsets expand in response to malaria in human tonsil and spleen organoids.PLoS pathogens · 2026Article
- Inhibitory NK receptor expression associates with altered antimalarial function of γδ T cells.PLoS pathogens · 2026Article
- Reinventing malaria control: hierarchical intervention strategies for African settings based on the microbiota-barrier-innate immunity axis.Frontiers in immunology · 2026Review
- Review
- Age is an intrinsic driver of inflammatory responses to malaria.Nature communications · 2025Article
- Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review.Pathogens (Basel, Switzerland) · 2025Article
- Vaccine-induced responses to R21/Matrix-M - an analysis of samples from a phase 1b age de-escalation, dose-escalation trial.Frontiers in immunology · 2025Article
- CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth.PLoS pathogens · 2025Article
- The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria.Nature reviews. Immunology · 2024Review
- Analysis of the Effector Functions of Vδ2 γδ T Cells and NK Cells against Cholangiocarcinoma Cells.Cells · 2024Article
- Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission.Biochemical Society transactions · 2024Review
- Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms.Nature communications · 2024Article
- Characteristics of splenic PD-1Immunologic research · 2024Article
- Chronic malaria exposure is associated with inhibitory markers on T cells that correlate with atypical memory and marginal zone-like B cells.Clinical and experimental immunology · 2024Article
- Phenotypic changes of γδ T cells inFrontiers in immunology · 2024Article
- Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets.Nature communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 3 countries.
Prasanna JagannathanDepartment of Medicine, Stanford University, Stanford, CA, USA. prasj@stanford.edu.ORCID 0000-0001-6305-758X
Fredrick LutwamaInfectious Diseases Institute, Kampala, Uganda.
Michelle J BoyleDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Felistas NankyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Lila A FarringtonDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Tara I McIntyreDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Katherine BowenDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Kate NaluwuInfectious Diseases Research Collaboration, Kampala, Uganda.
Mayimuna NalubegaInfectious Diseases Research Collaboration, Kampala, Uganda.
Kenneth MusinguziInfectious Diseases Research Collaboration, Kampala, Uganda.
Esther SikyomuInfectious Diseases Research Collaboration, Kampala, Uganda.
Rachel BudkerDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Agaba KatureebeInfectious Diseases Research Collaboration, Kampala, Uganda.
John RekInfectious Diseases Research Collaboration, Kampala, Uganda.
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Grant DorseyDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Moses R KamyaMakerere University College of Health Sciences, Kampala, Uganda.
Margaret E FeeneyDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA. margaret.feeney@ucsf.edu.
University of California, San Francisco · USInfectious Diseases Research Collaboration · UGBurnet Institute · AUInfectious Diseases Institute · UGMakerere University · UG
Funding
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi · 1988 to 2026
$93.6MTransmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3MThe role of γδ T cells in fetal and infant immune defense against malariaR01AI093615 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2011 to 2025
$9.1MMentoring Translational Researchers for Careers in Pediatric Global HealthK24AI113002 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2014 to 2023
$1.9MImmunologic Consequences of Highly Effective Antimalarial ChemopreventionK23AI100949 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAGANNATHAN, PRASANNA · 2012 to 2016
$657kPlasmodium Falciparum Infection and Interference with Effective B Cell MemoryR21AI107200 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENHOUSE, BRYAN R · 2014 to 2015
$435kNIAID NIH HHS K23 AI100949NIAID NIH HHS K24 AI113002NIAID NIH HHS P30 AI027763NIAID NIH HHS R01 AI093615NIAID NIH HHS R21 AI107200NIAID NIH HHS U19 AI089674
Abstract
Vδ2
Indexed as
Age FactorsBiomarkersChildChild, PreschoolCytokinesHumansLymphocyte CountMalariaParasitemiaPlasmodium falciparumReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesBiomarkersCytokinesReceptors, Antigen, T-Cell, gamma-delta
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.