Evidence map›Paper›PMID 28904195›Full record

ArticleJournal of virology2017

Vector Order Determines Protection against Pathogenic Simian Immunodeficiency Virus Infection in a Triple-Component Vaccine by Balancing CD4

Ulrike Sauermann, Antonia Radaelli, Nicole Stolte-Leeb, Katharina Raue, Massimiliano Bissa, Carlo Zanotto, Michael Krawczak, Matthias Tenbusch, Klaus Überla, Brandon F Keele and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Non-Human Primate-Derived Adenoviruses for Future Use as Oncolytic Agents?International journal of molecular sciences · 2020
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ulrike SauermannUnit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany.
Antonia RadaelliDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Nicole Stolte-LeebUnit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany.
Katharina RaueUnit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany.
Massimiliano BissaDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Carlo ZanottoDepartment of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy.
Michael KrawczakInstitute of Medical Informatics and Statistics, Christian-Albrechts University, Kiel, Germany.
Matthias TenbuschDepartment of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
Klaus ÜberlaUniversity Hospital Erlangen, Institute of Clinical and Molecular Virology, Erlangen, Germany.
Brandon F KeeleAIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Carlo De Giuli MorghenDepartment of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy.
Sieghart SopperClinic for Hematology and Oncology, Medical University Innsbruck, Tyrolean Cancer Research Center, Innsbruck, Austria.
Christiane Stahl-HennigUnit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany stahlh@dpz.eu.

Funding

CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

An effective AIDS vaccine should elicit strong humoral and cellular immune responses while maintaining low levels of CD4

Indexed as

AdenoviridaeAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesChemokine CXCL10Fowlpox virusFusion Proteins, gag-polGene Products, envGenetic VectorsImmunity, CellularImmunity, HumoralMacaca mulattaSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusVaccinationChemokine CXCL10Fusion Proteins, gag-polGene Products, envSAIDS VaccinesAIDS vaccineinnate immunityrecombinant adenovirusrecombinant fowlpox virusrepeated low-dose challengeSCIVsimian immunodeficiency virusSIV

Identifiers

PMID28904195
PMCPMC5686736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.