Evidence map›Paper›PMID 28904181›Full record

ReviewJournal of clinical microbiology2017

Progress and Challenges towards Point-of-Care Diagnostic Development for Dengue.

Junxiong Pang, Po Ying Chia, David C Lye, Yee Sin Leo

Abstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  19. NS1 Recombinant Proteins Are Efficiently Produced inDiagnostics (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junxiong PangInstitute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore pangv@hotmail.com.
Po Ying ChiaInstitute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
David C LyeInstitute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Yee Sin LeoInstitute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue detection strategies involve viral RNA, antigen, and/or antibody detection. Each strategy has its advantages and disadvantages. Optimal, user-friendly, rapid diagnostic tests based on immunochromatographic assays are pragmatic point-of-care tests (POCTs) in regions where dengue is endemic where there are limited laboratory capabilities and optimal storage conditions. Increasingly, there is a greater public health significance for a multiplexing assay that differentiates dengue from Zika or pathogens with similar clinical presentations. Although there have been many assay/platform developments toward POCTs, independent validation and implementation remain very limited. This review highlights the current key progress and challenges toward the development of a dengue POCT.

Indexed as

DengueDiagnostic Tests, RoutineHumansPoint-of-Care Systemsbiotechnologyclinical diagnosisdengue feverdiagnostics toolsflavivirusneutralizing antibodiespoint-of-care testserologyviral clearance

Identifiers

PMID28904181
PMCPMC5703800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.