SynthesisEvidence-based mental health2018
WHO Mental Health Gap Action Programme (mhGAP) Intervention Guide: a systematic review of evidence from low and middle-income countries.
Synthesis in Evidence-based mental health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04671225 (Psychoeducation for Patients With Bipolar Disorder in Rwanda), which is not on this map. Cited by 177 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychoeducation for Patients With Bipolar Disorder in Rwanda
Who cites it
177 citing papers in PubMed, 12 syntheses or guidelines pooled it.
- Poverty-reduction interventions combined with psychological interventions: A systematic literature review.Scientific reports · 2025Pooled it
- Health Professionals' Attitudes Towards Traditional Healing for Mental Illness: A Systematic Review.International journal of mental health nursing · 2025Pooled it
- Behavioral Activation Disseminated by Non-Mental Health Professionals, Paraprofessionals, and Peers: A Systematic Review.Behavior therapy · 2023Pooled it
- Mental Health Gap Action Programme intervention Guide (mhGAP-IG) for Child and Adolescent Mental Health in Low- and Middle-Income Countries (LMIC): A Systematic Review.Community mental health journal · 2023Pooled it
- Psychometric Validation of a Combined Assessment for Anxiety and Depression in Primary Care in Mozambique (CAD-MZ).Assessment · 2022Pooled it
- Prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries: a meta-review.BMJ open · 2022Pooled it
- Under detection of depression in primary care settings in low and middle-income countries: a systematic review and meta-analysis.Systematic reviews · 2022Pooled it
- Screening programs for common maternal mental health disorders among perinatal women: report of the systematic review of evidence.BMC psychiatry · 2022Pooled it
- Sleep Disorders in Early Childhood and the Development of Mental Health Problems in Adolescents: A Systematic Review of Longitudinal and Prospective Studies.International journal of environmental research and public health · 2021Pooled it
- Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries.The Cochrane database of systematic reviews · 2021Pooled it
- Implementation and use of the Mental Health Gap Action Programme Intervention Guide (mhGAP-IG): A review of the grey literature.Journal of global health · 2021Pooled it
- Reducing mental health-related stigma in primary health care settings in low- and middle-income countries: a systematic review.Epidemiology and psychiatric sciences · 2018Pooled it
- Trial
- Predictors of receiving a diagnosis, referral and treatment of depression in people on antiretroviral therapy in South African primary care: a secondary analysis of data from a randomised trial.Tropical medicine & international health : TM & IH · 2020Trial
- Evaluation of Proactive Community Case Detection to Increase Help Seeking for Mental Health Care: A Pragmatic Randomized Controlled Trial.Psychiatric services (Washington, D.C.) · 2020Trial
- Can General Practitioners manage mental disorders in primary care? A partially randomised, pragmatic, cluster trial.PloS one · 2019Trial
- "We find what we look for, and we look for what we know": factors interacting with a mental health training program to influence its expected outcomes in Tunisia.BMC public health · 2018Trial
- Adaptation and pilot implementation of the WHO guideline on digital intervention to strengthen mental health systems in Lagos state, Nigeria.Health research policy and systems · 2026Article
- Effectiveness of a brief depression training program to primary care personnel for people with type 2 diabetes mellitus and depression in India.Indian journal of psychiatry · 2026Article
- Global burden of mental disorders among women of child-bearing age, 1990-2021, with projections to 2050.European archives of psychiatry and clinical neuroscience · 2026Article
117 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
questionDespite mental, neurological and substance use (MNS) disorders being highly prevalent, there is a worldwide gap between service need and provision. WHO launched its Mental Health Gap Action Programme (mhGAP) in 2008, and the Intervention Guide (mhGAP-IG) in 2010. mhGAP-IG provides evidence-based guidance and tools for assessment and integrated management of priority MNS disorders in low and middle-income countries (LMICs), using clinical decision-making protocols. It targets a non-specialised primary healthcare audience, but has also been used by ministries, non-governmental organisations and academics, for mental health service scale-up in 90 countries. This review aimed to identify evidence to date for mhGAP-IG implementation in LMICs. STUDY SELECTION AND ANALYSIS: We searched MEDLINE, Embase, PsycINFO, Web of Knowledge/Web of Science, Scopus, CINAHL, LILACS, SciELO/Web of Science, Cochrane, Pubmed databases and Google Scholar for studies reporting evidence, experience or evaluation of mhGAP-IG in LMICs, in any language. Data were extracted from included papers, but heterogeneity prevented meta-analysis.
findingsWe conducted a systematic review of evidence to date, of mhGAP-IG implementation and evaluation in LMICs. Thirty-three included studies reported 15 training courses, 9 clinical implementations, 3 country contextualisations, 3 economic models, 2 uses as control interventions and 1 use to develop a rating scale. Our review identified the importance of detailed reports of contextual challenges in the field, alongside detailed protocols, qualitative studies and randomised controlled trials.
conclusionsThe mhGAP-IG literature is substantial, relative to other published evaluations of clinical practice guidelines: an important contribution to a neglected field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.