Evidence map›Paper›PMID 28903830›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2017

An Efficient, Simple, and Noninvasive Procedure for Genotyping Aquatic and Nonaquatic Laboratory Animals.

Morihiro Okada, Thomas C Miller, Julia Roediger, Yun-Bo Shi, Joseph Mat Schech

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Morihiro OkadaSection on Molecular Morphogenesis, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Thomas C MillerSection on Molecular Morphogenesis, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Julia RoedigerSection on Molecular Morphogenesis, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Yun-Bo ShiSection on Molecular Morphogenesis, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Joseph Mat SchechAnimal Program, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland;, Email: schechj@dir6.nichd.nih.gov.

Funding

Regulation of stem cell development during tissue remodelingZIAHD008858 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SHI, YUN-BO · 2009 to 2025
$15.2M
Molecular mechanism of thyroid hormone receptor function during metamorphosisZIAHD001901 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SHI, YUN-BO · 2009 to 2025
$13.1M
6 · The paper itself

Abstract

Various animal models are indispensible in biomedical research. Increasing awareness and regulations have prompted the adaptation of more humane approaches in the use of laboratory animals. With the development of easier and faster methodologies to generate genetically altered animals, convenient and humane methods to genotype these animals are important for research involving such animals. Here, we report skin swabbing as a simple and noninvasive method for extracting genomic DNA from mice and frogs for genotyping. We show that this method is highly reliable and suitable for both immature and adult animals. Our approach allows a simpler and more humane approach for genotyping vertebrate animals.

Indexed as

GenotypeSkinAnimalsAnimals, LaboratoryBiomedical ResearchDNAMiceDNA

Identifiers

PMID28903830
PMCPMC5605183

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.