Evidence map›Paper›PMID 28903424›Full record

ArticleOncotarget2017

Identification and characterization of a novel

Massimo Milione, Elena Ardini, Jason Christiansen, Emanuele Valtorta, Silvio Veronese, Roberta Bosotti, Alessio Pellegrinelli, Adele Testi, Filippo Pietrantonio, Giovanni Fucà and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Article
  8. Article
  9. How selecting best therapy for metastaticTranslational lung cancer research · 2020
    Review
  10. Review
  11. Review
  12. Article
  13. Identifying patients with NTRK fusion cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2019
    Review
  14. Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2019
    Review
  15. The Landscape of Actionable Gene Fusions in Colorectal Cancer.International journal of molecular sciences · 2019
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Brazilian Expert Consensus for NTRK Gene Fusion Testing in Solid Tumors.Clinical pathology (Thousand Oaks, Ventura County, Calif.)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Massimo Milione1st Division of Pathology, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Elena ArdiniNerviano Medical Sciences S.r.l., Milan, Italy.
Jason ChristiansenIgnyta, Inc., San Diego, CA, United States of America.
Emanuele ValtortaDivision of Pathology, Department of Laboratory Medicine, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Silvio VeroneseDivision of Pathology, Department of Laboratory Medicine, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Roberta BosottiNerviano Medical Sciences S.r.l., Milan, Italy.
Alessio Pellegrinelli1st Division of Pathology, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Adele Testi1st Division of Pathology, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Filippo PietrantonioDipartimento di Oncologia e Emato-Oncologia, Università degli Studi di Milano, Milan, Italy.
Giovanni FucàMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Ge WeiIgnyta, Inc., San Diego, CA, United States of America.
Danielle MurphyIgnyta, Inc., San Diego, CA, United States of America.
Salvatore SienaDivision of Pathology, Department of Laboratory Medicine, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Antonella IsacchiNerviano Medical Sciences S.r.l., Milan, Italy.
Filippo De BraudDipartimento di Oncologia e Emato-Oncologia, Università degli Studi di Milano, Milan, Italy.
Ignyta (United States) · USFondazione IRCCS Istituto Nazionale dei Tumori · ITNerviano Medical Sciences · ITUniversity of Milan · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In colorectal cancer patients, chromosomal rearrangements involving

Indexed as

CRCentrectinibNTRK1rearrangementTRKA

Identifiers

PMID28903424
PMCPMC5589663
OpenAlexW2736521669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.