Evidence map›Paper›PMID 28903403›Full record

ArticleOncotarget2017

Cofilin-1 and phosphoglycerate kinase 1 as promising indicators for glioma radiosensibility and prognosis.

Wenbo Sun, Hua Yan, Chunfa Qian, Chenhan Wang, Mengjie Zhao, Yuchi Liu, Yujie Zhong, Hongyi Liu, Hong Xiao

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The effect of CELLFOODTherapeutic advances in medical oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wenbo Sun *Department of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Hua Yan *Department of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Chunfa QianDepartment of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Chenhan WangDepartment of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Mengjie ZhaoDepartment of Neuro-Psychiatric Institute, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Yuchi LiuDepartment of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Yujie ZhongDepartment of Neuro-Psychiatric Institute, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Hongyi LiuDepartment of Neurosurgery, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Hong XiaoDepartment of Neuro-Psychiatric Institute, Nanjing Medical University Affiliated Brain Hospital, Nanjing, China.
Nanjing Brain Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is a primary malignancy in central nervous system. Radiotherapy has been used as one of the standard treatments for glioma for decades. Since radioresistance can reduce the curative efficacy of radiotherapy in glioma, investigating the cause of radioresistance and predicting the tumour radiosensibility appeared particularly important. We previously reported that CFL1 and PGK1 are over-expressed in radioresistant U251 glioma cells. In this study, the level of CFL1 and PGK1 of 113 glioma tissues were measured by ELISA method. The relevance of the expression of these two proteins to radiosensibility was analyzed by mean test and multivariate logistic regression. The survival analysis was carried out in 85 irradiated patients and 105 followed-up patients respectively. The relationship between protein expression and clinical parameters was explored in overall 113 patients, and the correlation between CFL1 and PGK1 were determined as well. Our results showed that the expression of CFL1 and PGK1 were significantly higher (

Indexed as

CFL1gliomaPGK1prognosisradiosensibility

Identifiers

PMID28903403
PMCPMC5589642
OpenAlexW2727638122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.