Evidence map›Paper›PMID 28903262›Full record

ArticleSensors (Basel, Switzerland)2007

Antimicrobial Peptides: New Recognition Molecules for Detecting Botulinum Toxins.

Nadezhda V Kulagina, George P Anderson, Frances S Ligler, Kara M Shaffer, Chris Rowe Taitt

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nadezhda V KulaginaCenter for Bio/Molecular Science & Engineering, Code 6900, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA.
George P AndersonCenter for Bio/Molecular Science & Engineering, Code 6900, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA.
Frances S LiglerCenter for Bio/Molecular Science & Engineering, Code 6900, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA.
Kara M ShafferCenter for Bio/Molecular Science & Engineering, Code 6900, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA.
Chris Rowe TaittCenter for Bio/Molecular Science & Engineering, Code 6900, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA. chris.taitt@nrl.navy.mil.
United States Naval Research Laboratory · USNaval Research Laboratory Center for Bio/Molecular Science and Engineering

Funding

Arrays of Receptors for Infectious Disease DiagnosisR01EB000680 · NIBIB · U.S. NAVAL RESEARCH LABORATORY · PI LIGLER, FRANCES S. · 2003 to 2005
$1.8M
NIBIB NIH HHS R01 EB000680
6 · The paper itself

Abstract

Many organisms secrete antimicrobial peptides (AMPs) for protection againstharmful microbes. The present study describes detection of botulinum neurotoxoids A, Band E using AMPs as recognition elements in an array biosensor. While AMP affinitieswere similar to those for anti-botulinum antibodies, differences in binding patterns wereobserved and can potentially be used for identification of toxoid serotype. Furthermore,some AMPs also demonstrated superior detection sensitivity compared to antibodies: toxoidA could be detected at 3.5 LD

Indexed as

Antimicrobial peptidearraybiosensorbotulinum toxindetection

Identifiers

PMID28903262
PMCPMC3965214
OpenAlexW2115024294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.