ArticleBrain, behavior, and immunity2018
Inflammatory dietary patterns and depressive symptoms in Italian older adults.
Article in Brain, behavior, and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Dietary inflammatory potential and the incidence of depression and anxiety: a meta-analysis.Journal of health, population, and nutrition · 2022Pooled it
- Dietary Inflammatory Potential and the Risk of Incident Depression in Adults: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Sex consideration in diet-biomarker-related indices: a systematic review.Public health nutrition · 2018Pooled it
- Sugar-sweetened beverage consumption and incident depression: an exploratory multi-omics analysis of candidate biological mediators.Nutrition journal · 2026Article
- Anti-inflammatory diet and mental health outcomes in an aging population: evidence from a preventive population-based target trial emulation.GeroScience · 2026Article
- Article
- Identifying leading anti-inflammatory dietary determinants of depression and loneliness in older adults.Brain, behavior, & immunity - health · 2025Article
- Associations between uric acid and depressive symptoms, and the mediating role of immunoinflammatory: Findings from rural older adults.Brain, behavior, & immunity - health · 2024Article
- Dietary Inflammatory Potential, Inflammation-Related Lifestyle Factors, and Incident Anxiety Disorders: A Prospective Cohort Study.Nutrients · 2023Article
- Association between empirical dietary inflammatory index, odds, and severity of anxiety disorders: A case-control study.Food science & nutrition · 2023Article
- Association of Proinflammatory Diet With Frailty Onset Among Adults With and Without Depressive Symptoms: Results From the Framingham Offspring Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Association between Dietary Patterns and the Risk of Depressive Symptoms in the Older Adults in Rural China.Nutrients · 2022Article
- Article
- Circulating Inflammation Markers Partly Explain the Link Between the Dietary Inflammatory Index and Depressive Symptoms.Journal of inflammation research · 2021Article
- Dietary patterns associated with inflammatory biomarkers in a Northern German population.European journal of nutrition · 2020Article
- Association of poorer dietary quality and higher dietary inflammation with greater symptom severity in depressed individuals with appetite loss.Journal of affective disorders · 2020Article
- The association between predicted inflammatory status and colorectal adenoma.Scientific reports · 2020Article
- Depression Relationship with Dietary Patterns and Dietary Inflammatory Index in Women: Result from Ravansar Cohort Study.Neuropsychiatric disease and treatment · 2020Article
- Increased Dietary Inflammatory Index Is Associated with Schizophrenia: Results of a Case-Control Study from Bahrain.Nutrients · 2019Article
- Perspective: The Dietary Inflammatory Index (DII)-Lessons Learned, Improvements Made, and Future Directions.Advances in nutrition (Bethesda, Md.) · 2019Article
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundOlder adults are more susceptible to higher inflammatory levels and depression. Moreover, diet may influence inflammation as well as depression but no previous study examined whether inflammatory dietary patterns are related to depression in an older population. To investigate the longitudinal association between inflammatory dietary patterns (using reduced rank regression (RRR)) and depressive symptoms in a population sample of Italian older adults.
methodsWe included 827 participants (aged≥65years) at baseline in 1998. Follow-up measurements were collected after 3, 6 and 9years. We used RRR to identify inflammatory dietary patterns at baseline. The Centre for Epidemiologic Studies Depression (CES-D) scale was used to assess depressive symptoms by using continuous scores and depression by using a cut-off point (CES-D≥20).
resultsWe identified two inflammatory dietary patterns using different sets of response variables. Dietary pattern I was related to inflammatory markers C-reactive protein (CRP), interleukin (IL)-6, tumor necrosis factor α and was characterized by high intakes of refined grains, sweet snacks, pasta and rice. After full adjustment for confounders, no longitudinal association was found when comparing extreme quartiles of this dietary pattern and depressive symptoms (Q1vs Q4, model 4: B=0.04, 95% CI: -0.06, 0.13) or depression (Q1vs Q4, model 4: OR=0.90, 95% CI: 0.55, 1.45). Dietary pattern II was related to inflammatory markers CRP, IL-18, IL-1β, IL-1 receptor antagonist and was characterized by high intakes of pasta, sugar-sweetened beverages, processed meat and chocolate and sweets. When comparing extreme quartiles, this dietary pattern was not longitudinally associated with depressive symptoms (Q1vs Q4, model 4: B=-0.04, 95% CI: -0.13, 0.05) but an inverse association was found for depression (Q1vs Q4, model 4: OR=0.56, 95% CI: 0.40, 0.94).
conclusionOur study does not support the hypothesis that dietary patterns linked to inflammatory markers are associated with higher depressive symptoms and higher depression incidence. However, dietary intake in our population of older adults was quite homogeneous which makes it difficult to show clear associations.
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