Evidence map›Paper›PMID 28902999›Full record

ArticleJournal of the American Chemical Society2017

Self-Assembled 2D Free-Standing Janus Nanosheets with Single-Layer Thickness.

Yiyang Lin, Michael R Thomas, Amy Gelmi, Vincent Leonardo, E Thomas Pashuck, Stephanie A Maynard, Ye Wang, Molly M Stevens

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. 2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Precise Epitaxial 1D and 2D Growth of Polyester-Based Materials in n-Alkanes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Shape-assisted self-assembly.Nature communications · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Crescent-Shaped Supramolecular Tetrapeptide Nanostructures.Journal of the American Chemical Society · 2020
    Article
  14. Iridescence in nematics: Photonic liquid crystals of nanoplates in absence of long-range periodicity.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  15. Peptide Tectonics: Encoded Structural Complementarity Dictates Programmable Self-Assembly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Review
  16. Article
  17. Article
  18. Supramolecular self assembly of nanodrill-like structures for intracellular delivery.Journal of controlled release : official journal of the Controlled Release Society · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiyang LinDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.ORCID 0000-0003-2017-190X
Michael R ThomasDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.ORCID 0000-0001-7795-9648
Amy GelmiDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.
Vincent LeonardoDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.
E Thomas PashuckDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.ORCID 0000-0003-2881-4965
Stephanie A MaynardDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.
Ye WangDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.
Molly M StevensDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London , Exhibition Road, London SW7 2AZ, U.K.ORCID 0000-0002-7335-266X

Funding

Biotechnology and Biological Sciences Research Council BB/L015129/1European Research Council 616417
6 · The paper itself

Abstract

We report the thermodynamically controlled growth of solution-processable and free-standing nanosheets via peptide assembly in two dimensions. By taking advantage of self-sorting between peptide β-strands and hydrocarbon chains, we have demonstrated the formation of Janus 2D structures with single-layer thickness, which enable a predetermined surface heterofunctionalization. A controlled 2D-to-1D morphological transition was achieved by subtly adjusting the intermolecular forces. These nanosheets provide an ideal substrate for the engineering of guest components (e.g., proteins and nanoparticles), where enhanced enzyme activity was observed. We anticipate that sequence-specific programmed peptides will offer promise as design elements for 2D assemblies with face-selective functionalization.

Indexed as

Molecular StructureNanostructuresParticle SizePeptidesThermodynamicsPeptides

Identifiers

PMID28902999
PMCPMC5632812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.