ArticlePLoS neglected tropical diseases2017
Melioidosis in lower provincial Cambodia: A case series from a prospective study of sepsis in Takeo Province.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Article
- Zoonotic neglected tropical diseases at the animal-human interface in the Greater Mekong Subregion: Two decades of surveillance in Laos and Cambodia.PLoS neglected tropical diseases · 2026Review
- Multilocus sequence typing of clinical Burkholderia pseudomallei isolates from Cambodia.PLoS neglected tropical diseases · 2024Article
- Case Report: Risk Factors Associated with Mortality in Adults with Burkholderia Pseudomallei Bacteremia: A Retrospective Case Series of Melioidosis in Cambodia.The American journal of tropical medicine and hygiene · 2024Article
- Host-response transcriptional biomarkers accurately discriminate bacterial and viral infections of global relevance.Scientific reports · 2023Article
- Screening tools for predicting mortality of adults with suspected sepsis: an international sepsis cohort validation study.BMJ open · 2023Article
- Showing the limitations of available phenotypic assays to detectAccess microbiology · 2023Article
- Burden and Risk Factors of Melioidosis in Southeast Asia: A Scoping Review.International journal of environmental research and public health · 2022Article
- Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins.Acta pharmaceutica Sinica. B · 2022Review
- Acute kidney injury and its outcomes in melioidosis.Journal of nephrology · 2021Observational
- An approach to rapidly assess sepsis through multi-biomarker host response using machine learning algorithm.Scientific reports · 2021Article
- Multiplexed cytokine detection using electrochemical point-of-care sensing device towards rapid sepsis endotyping.Biosensors & bioelectronics · 2021Review
- An Observational Study of Sepsis in Takeo Province Cambodia: An in-depth examination of pathogens causing severe infections.PLoS neglected tropical diseases · 2020Observational
- Human Melioidosis.Clinical microbiology reviews · 2020Review
- GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.Antimicrobial agents and chemotherapy · 2019Article
- Retrospective Analysis of Fever and Sepsis Patients from Cambodia Reveals Serological Evidence of Melioidosis.The American journal of tropical medicine and hygiene · 2018Article
- A Report from the Cambodia Training Event for Awareness of Melioidosis (C-TEAM), October 2017.Tropical medicine and infectious disease · 2018Article
- Hyponatremia in Melioidosis: Analysis of 10-year Data from a Hospital-Based Registry.Journal of global infectious diseasesArticle
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13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Melioidosis is a severe infectious disease caused by the gram-negative soil bacterium Burkholderia pseudomallei. Melioidosis is well known to be a major cause of morbidity and mortality in Southeast Asia, particularly in Thailand. However, melioidosis remains underreported in surrounding areas such as Cambodia. We report a case series of melioidosis in seven patients from Takeo Province, Cambodia. The patients, aged 24-65 years, were enrolled from May 2014 to May 2015 during a one year prospective study of sepsis at Takeo Provincial Hospital. They presented with fever, rigors, dyspnea, fatigue, diaphoresis, productive cough, and skin abscesses. Six of the seven patients were also hyponatremic. B. pseudomallei was cultured from the blood of six patients and the sputum of one patient. In this manuscript, we provide a detailed description of the clinical presentation, case management and laboratory confirmation of B. pseudomallei, as well as discuss the difficulties of identifying and treating melioidosis in low resource settings.
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