Evidence map›Paper›PMID 28902704›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

HIV Preexposure Prophylaxis Implementation at Local Health Departments: A Statewide Assessment of Activities and Barriers.

Helen L Zhang, Sarah K Rhea, Christopher B Hurt, Victoria L Mobley, Heidi Swygard, Arlene C Seña, Mehri S McKellar

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Readiness to Provide Oral and Injectable PrEP for Sexual and Gender Minority Youth Among Healthcare Providers and Clinics in the U.S. Northeast.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helen L ZhangDepartment of Medicine, Duke University Medical Center, Durham, NC.
Sarah K RheaNorth Carolina Department of Health and Human Services, Raleigh, NC.
Christopher B HurtDepartment of Medicine, Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Victoria L MobleyNorth Carolina Department of Health and Human Services, Raleigh, NC.
Heidi SwygardNorth Carolina Department of Health and Human Services, Raleigh, NC.
Arlene C SeñaDepartment of Medicine, Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Mehri S McKellarDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Home-Collected Blood Spots to Increase HIV Test Frequency among Young Black MSMK23MH099941 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HURT, CHRISTOPHER BROWNING · 2013 to 2017
$837k
NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI064518NIMH NIH HHS K23 MH099941
6 · The paper itself

Abstract

backgroundExpanding access to HIV preexposure prophylaxis (PrEP) could help reduce rates of HIV infection in the United States. This study characterizes activities and barriers to PrEP implementation at local health departments (LHDs) in North Carolina (NC), which contains a large rural population.

methodsIn May 2016, a web-based survey was distributed to health directors of all county and district health departments in NC to assess PrEP-related activities, perceived barriers to PrEP implementation, and desired PrEP-related resources.

resultsOf 85 LHDs in NC, 56 (66%) responded to the survey. Of these, 2 (4%) reported PrEP prescribing and 7 (13%) externally referred for PrEP services. Among the 54 departments not prescribing PrEP, the most frequently cited reasons were cost concerns (n = 25, 46%), lack of formal prescribing protocols (n = 21, 39%), and belief that PrEP would be better managed at primary care or specialty clinics (n = 19, 35%). Among the 47 departments not prescribing or referring clients for PrEP, the most frequently cited reasons for the lack of PrEP referral were the absence of local PrEP providers (n = 29, 62%), lack of PrEP knowledge among staff (n = 13, 28%), and perceived lack of PrEP candidates (n = 12, 26%). The most frequently requested PrEP-related resources included training to help identify PrEP candidates (n = 39, 70%) and training on PrEP prescribing and management (n = 38, 68%).

conclusionsPrEP prescribing and referral among LHDs in NC remains extremely limited. Increased PrEP-related training and support for LHD-based providers could enhance PrEP access, especially in rural and underserved areas.

Indexed as

Attitude of Health PersonnelHealth Plan ImplementationPre-Exposure ProphylaxisAdultAnti-HIV AgentsFemaleHealth PersonnelHIV InfectionsHumansMaleMiddle AgedNorth CarolinaReferral and ConsultationSurveys and QuestionnairesAnti-HIV Agents

Identifiers

PMID28902704
PMCPMC5720898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.