Evidence map›Paper›PMID 28902683›Full record

Trial reportMedicine and science in sports and exercise2018

Exercise Oscillatory Ventilation: Interreviewer Agreement and a Novel Determination.

Clinton A Brawner, Jonathan K Ehrman, Jonathan Myers, Paul Chase, Baruch Vainshelboim, Shadi Farha, Matthew A Saval, Rita McGuire, Bunny Pozehl, Steven J Keteyian

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine and science in sports and exercise, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01658670 (HEART Camp), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01658670 nacompletednot on this map

HEART Camp: Promoting Adherence to Exercise in Patients With Heart Failure

TypeinterventionalSponsorUniversity of NebraskaRan2012 to 2018Enrolled245ConditionsHeart FailureArmsEnhanced Usual Care Group, HEART Camp (HC) Intervention Group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Clinton A BrawnerDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Jonathan K EhrmanDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Jonathan MyersDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Paul ChaseDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Baruch VainshelboimDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Shadi FarhaDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Matthew A SavalDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Rita McGuireDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Bunny PozehlDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Steven J KeteyianDivision of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI.
Henry Ford Hospital · USVA Palo Alto Health Care System · USOhio University · USUniversity of Nebraska Medical Center · US

Funding

Heart Camp: Promoting Adherence to Exercise in Patients with Heart FailureR01HL112979 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI POZEHL, BUNNY · 2012 to 2016
$3.3M
Senior Research Career ScientistIK6RX002477 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI MYERS, JONATHAN N. · 2017 to 2025
–
NHLBI NIH HHS R01 HL112979RRD VA IK6 RX002477
6 · The paper itself

Abstract

introductionDetermination of exercise oscillatory ventilation (EOV) is subjective, and the interreviewer agreement has not been reported. The purposes of this study were, among patients with heart failure (HF), as follows: 1) to determine the interreviewer agreement for EOV and 2) to describe a novel, objective, and quantifiable measure of EOV.

methodsThis was a secondary analysis of the HEART Camp: Promoting Adherence to Exercise in Patients with Heart Failure study. EOV was determined through a blinded review by six individuals on the basis of their interpretation of the EOV literature. Interreviewer agreement was assessed using Fleiss kappa (κ). Final determination of EOV was based on agreement by four of the six reviewers. A new measure (ventilation dispersion index; VDI) was calculated for each test, and its ability to predict EOV was assessed with the receiver operator characteristics curve.

resultsAmong 243 patients with HF (age, 60 ± 12 yr; 45% women), the interreviewer agreement for EOV was fair (κ = 0.303) with 10-s discrete data averages and significantly better, but only moderate (κ = 0.429) with 30-s rolling data averages. Prevalence rates of positive and indeterminate EOVs were 18% and 30% with the 10-s discrete averages and 14% and 13% with the 30-s rolling averages, respectively. VDI was strongly associated with EOV, with areas under the receiver operator characteristics curve of 0.852 to 0.890.

conclusionsInterreviewer agreement for EOV in patients with HF is fair to moderate, which can negatively affect risk stratification. VDI has strong predictive validity with EOV; as such, it might be a useful measure of prognosis in patients with HF.

Indexed as

ExercisePulmonary VentilationRespirationAgedExercise TestFemaleHeart FailureHumansMaleMiddle Aged

Identifiers

PMID28902683
PMCPMC5772890
OpenAlexW2755504557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.