ArticleInternational journal of environmental research and public health2017
Distribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain.
Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- A systematic review of the toxic potential of parabens in fish.Frontiers in toxicology · 2024Pooled it
- Advanced Materials-Based Nanofiltration Membranes for Efficient Removal of Organic Micropollutants in Water and Wastewater Treatment.Membranes · 2025Review
- Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025Review
- Article
- Exposure assessment of dairy cows to parabens using hair samples analysis.Scientific reports · 2024Article
- Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index.Nutrients · 2023Article
- Benzophenones in the Environment: Occurrence, Fate and Sample Preparation in the Analysis.Molecules (Basel, Switzerland) · 2023Review
- Article
- The Presence of Triclosan in Human Hair Samples in Poland-A Pilot Study.International journal of environmental research and public health · 2022Article
- Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells.Current research in toxicology · 2022Article
- The development and function of the brain barriers - an overlooked consideration for chemical toxicity.Frontiers in toxicology · 2022Review
- Prenatal Exposure to Triclocarban Impairs ESR1 Signaling and Disrupts Epigenetic Status in Sex-Specific Ways as Well as Dysregulates the Expression of Neurogenesis- and Neurotransmitter-Related Genes in the Postnatal Mouse Brain.International journal of molecular sciences · 2021Article
- UV-filter pollution: current concerns and future prospects.Environmental monitoring and assessment · 2021Review
- Overview of the Mechanisms of Action of Selected Bisphenols and Perfluoroalkyl Chemicals on the Male Reproductive Axes.Frontiers in genetics · 2021Review
- Exposure to Endocrine Disrupting Chemicals in the Dutch general population is associated with adiposity-related traits.Scientific reports · 2020Article
- Thyroid Hormone and Neural Stem Cells: Repair Potential Following Brain and Spinal Cord Injury.Frontiers in neuroscience · 2020Review
- Article
- Triclocarban Disrupts the Epigenetic Status of Neuronal Cells and Induces AHR/CAR-Mediated Apoptosis.Molecular neurobiology · 2019Article
- Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain.Scientific reports · 2018Article
- Does the prenatal bisphenol A exposure alter DNA methylation levels in the mouse hippocampus?: An analysis using a high-sensitivity methylome technique.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-persistent endocrine disrupting chemicals (npEDCs) can affect multiple organs and systems in the body. Whether npEDCs can accumulate in the human brain is largely unknown. The major aim of this pilot study was to examine the presence of environmental phenols and parabens in two distinct brain regions: the hypothalamus and white-matter tissue. In addition, a potential association between these npEDCs concentrations and obesity was investigated. Post-mortem brain material was obtained from 24 individuals, made up of 12 obese and 12 normal-weight subjects (defined as body mass index (BMI) > 30 and BMI < 25 kg/m², respectively). Nine phenols and seven parabens were measured by isotope dilution TurboFlow-LC-MS/MS. In the hypothalamus, seven suspect npEDCs (bisphenol A, triclosan, triclocarban and methyl-, ethyl-, n-propyl-, and benzyl paraben) were detected, while five npEDCs (bisphenol A, benzophenone-3, triclocarban, methyl-, and n-propyl paraben) were found in the white-matter brain tissue. We observed higher levels of methylparaben (MeP) in the hypothalamic tissue of obese subjects as compared to controls (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.