Evidence map›Paper›PMID 28902140›Full record

ArticleNutrients2017

Iron Absorption from Three Commercially Available Supplements in Gastrointestinal Cell Lines.

Francesca Uberti, Vera Morsanuto, Sabrina Ghirlanda, Claudio Molinari

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 27 citations in OpenAlex.

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  7. Combined Effects of Diosmin, Hesperidin,International journal of molecular sciences · 2025
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  16. The Role ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francesca UbertiLaboratory of Physiology, Department of Translational Medicine, University of Eastern Piedmont, via Solaroli 17, 28100 Novara, Italy. francesca.uberti@med.uniupo.it.
Vera MorsanutoLaboratory of Physiology, Department of Translational Medicine, University of Eastern Piedmont, via Solaroli 17, 28100 Novara, Italy. vera.morsanuto@med.uniupo.it.
Sabrina GhirlandanoiVita s.r.l.s. Spin-Off of University of Eastern Piedmont, via A. Canobio 4/6, 28100 Novara, Italy. info@noivita.it.
Claudio MolinariLaboratory of Physiology, Department of Translational Medicine, University of Eastern Piedmont, via Solaroli 17, 28100 Novara, Italy. claudio.molinari@med.uniupo.it.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compares the absorption characteristics of two iron-based dietary supplements and their biocompatibility to bisglycinate iron, a common chelated iron form. The Caco-2 cell line-a model of human intestinal absorption-and GTL-16 cell line-a model of gastric epithelial cells-were used to perform the experiments; in the first experiments, the kinetics of absorption have been evaluated analyzing the divalent metal transporter 1 (DMT1) expression. Three different iron combinations containing 50 µM iron (named Fisioeme

Indexed as

Dietary SupplementsBiological AvailabilityCaco-2 CellsCation Transport ProteinsCell Line, TumorCell SurvivalEpithelial CellsGene Expression RegulationHumansIntestinal AbsorptionIntestinal MucosaIntestinesIronSolute Carrier Family 11, Member 2Cation Transport ProteinsIronSolute Carrier Family 11, Member 2Caco-2 permeabilityDMT1 receptorGTL-16 permeabilityiron mechanismsiron metabolism

Identifiers

PMID28902140
PMCPMC5622768
OpenAlexW2756354197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.