Evidence map›Paper›PMID 28902127›Full record

ArticleInternational journal of molecular sciences2017

Altered Gene Expression of RNF34 and PACAP Possibly Involved in Mechanism of Exercise-Induced Analgesia for Neuropathic Pain in Rats.

Shintaro Yamaoka, Yusuke Oshima, Hideki Horiuchi, Tadao Morino, Masayuki Hino, Hiromasa Miura, Tadanori Ogata

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Protective Effects of PACAP in a Rat Model of Diabetic Neuropathy.International journal of molecular sciences · 2021
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shintaro YamaokaDepartment of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Ehime, Japan. shinyama@m.ehime-u.ac.jp.
Yusuke OshimaTranslational Research Center, Ehime University Hospital, Shitsukawa, Toon 791-0295, Ehime, Japan. oshima-ehm@umin.ac.jp.
Hideki HoriuchiOzu Municipal Hospital, Nishiozu, Ozu 795-8501, Ehime, Japan. horiuchiehime@gmail.com.
Tadao MorinoDepartment of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Ehime, Japan. morino@m.ehime-u.ac.jp.
Masayuki HinoDepartment of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Ehime, Japan. hino@m.ehime-u.ac.jp.ORCID 0000-0002-8634-022X
Hiromasa MiuraDepartment of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Ehime, Japan. miura@m.ehime-u.ac.jp.ORCID 0000-0002-5643-8023
Tadanori OgataDepartment of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon 791-0295, Ehime, Japan. ogata@m.ehime-u.ac.jp.
Ehime University · JPEhime University Hospital · JPOtsu Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the availability of several modalities of treatment, including surgery, pharmacological agents, and nerve blocks, neuropathic pain is often unresponsive and sometimes progresses to intractable chronic pain. Although exercise therapy is a candidate for treatment of neuropathic pain, the mechanism underlying its efficacy has not been elucidated. To clarify the molecular mechanism for pain relief induced by exercise, we measured

Indexed as

Gene Expression RegulationAnalgesiaAnimalsCarrier ProteinsDisease Models, AnimalExercise TestFemaleNeuralgiaPain ManagementPhysical Conditioning, AnimalPituitary Adenylate Cyclase-Activating PolypeptideRatsRNA, MessengerSpinal CordSpinal Cord Dorsal HornSpinal Cord InjuriesCarrier ProteinsPituitary Adenylate Cyclase-Activating PolypeptideRNA, Messengerexercise therapyLMDneuropathic painPACAPRNA sequenceRNF34SNL model

Identifiers

PMID28902127
PMCPMC5618611
OpenAlexW2755037163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.