ArticleEuropean journal of clinical nutrition2017
Raw BIA variables are predictors of muscle strength in patients with chronic obstructive pulmonary disease.
Article in European journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Frailty in COPD: Clinical Impact, Diagnosis, Biomarkers, and Management Strategies.International journal of chronic obstructive pulmonary disease · 2025Pooled it
- Bioelectrical impedance phase angle in sport: a systematic review.Journal of the International Society of Sports Nutrition · 2019Pooled it
- Small RNA Profiles of Serum-Derived Extracellular Vesicles in the Comorbid Condition of Frailty and Obstructive Pulmonary Disease: An Observational, Cross-Sectional Study.Biomolecules · 2025Observational
- Association Between Muscle Quality and Quantitative Changes According to Nutritional Intake Differences in Patients Recovering From Trauma.Clinical nutrition research · 2025Article
- Association between bioelectrical impedance analysis parameters and muscle-related measurements obtained using a non-diagnostic ultrasound-based technique.Journal of translational medicine · 2025Article
- The association between muscle strength and z scores of pulmonary function.Scientific reports · 2025Article
- Muscle Wasting and Treatment of Dyslipidemia in COPD: Implications for Patient Management.Biomedicines · 2025Review
- Analysis of Body Fluid Distribution, Phase Angle and Its Association With Maximal Oxygen Consumption in Facioscapulohumeral Dystrophy: An Observational Study.Health science reports · 2025Article
- Bioelectrical impedance analysis-derived phase angle predicts possible Sarcopenia in patients on maintenance hemodialysis: a retrospective study.BMC nephrology · 2024Article
- Association of phase angle with sarcopenia and muscle function in patients with COPD: a case-control study.BMC pulmonary medicine · 2024Article
- Association of phase angle with sarcopenia in patients undergoing maintenance hemodialysis: A case-control study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- The effects of a physical exercise program in Chinese kidney transplant recipients: a prospective randomised controlled trial.Clinical kidney journal · 2023Article
- Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment.Reviews in endocrine & metabolic disorders · 2023Review
- Phase angle in assessment and monitoring treatment of individuals with respiratory disease.Reviews in endocrine & metabolic disorders · 2023Review
- Phase Angle Is Associated With Handgrip Strength in Older Patients With Heart Failure.Annals of rehabilitation medicine · 2023Article
- Association of phase angle with sarcopenia in chronic musculoskeletal pain patients: a retrospective study.Journal of orthopaedic surgery and research · 2023Article
- Body Composition and COPD: A New Perspective.International journal of chronic obstructive pulmonary disease · 2023Review
- Relationship between Nutritional Status, Body Composition, Muscle Strength, and Functional Recovery in Patients with Proximal Femur Fracture.Nutrients · 2022Article
- Reference Data of Phase Angle Using Bioelectrical Impedance Analysis in Overweight and Obese Chinese.Frontiers in endocrinology · 2022Article
- Correlation of the Phase Angle with Muscle Ultrasound and Quality of Life in Obese Females.Disease markers · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesAlthough loss of fat-free mass (FFM) and reduced muscle strength are highly prevalent in chronic obstructive pulmonary disease (COPD), only few data are available on the relationships of handgrip strength (HGS) and respiratory muscle strength with body composition in such disease. In particular, we aimed to assess whether raw bioelectrical impedance (BIA) variables were independent predictors of muscle strength in COPD patients, possibly more significant than anthropometric variables and BIA-based estimates of FFM. SUBJECTS/
methodsTwo hundred and thirty-seven COPD patients (161 males and 76 females) underwent respiratory, anthropometric, BIA, HGS and respiratory muscle strength (maximum inspiratory or expiratory pressure=MIP and MEP) measurements. Bioimpedance index (BI index=height square/whole-body impedance) and phase angle (PhA) were considered as raw BIA variables. FFM was estimated using three disease-specific BIA equations.
resultsIn COPD patients a stronger correlation was observed between HGS and PhA compared to the ones with anthropometric variables or FFM estimates. Multiple regression analysis showed that combining BI index and PhA (plus age in male patients) accounted for 50.2% and 42.6% of the variance in HGS in male and female patients, respectively. Similarly, BI index and PhA emerged as predictors of both MIP and MEP in males, while in females MIP was related only to PhA and MEP only to BI index.
conclusionsRaw BIA variables are independent and valuable predictors of HGS and respiratory muscle strength in COPD patients. BI index and PhA could provide useful information for evaluating body composition and better assessing muscle strength and physical fitness in COPD.
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