Evidence map›Paper›PMID 28901329›Full record

ArticleThe Journal of antibiotics2017

Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.

Toshihiko Nogawa, Naoki Kato, Takeshi Shimizu, Akiko Okano, Yushi Futamura, Shunji Takahashi, Hiroyuki Osada

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Toshihiko NogawaRIKEN Center for Sustainable Resource Science, Chemical Biology Research Group, Wako, Saitama, Japan.
Naoki KatoRIKEN Center for Sustainable Resource Science, Natural Product Biosynthesis Research Unit, Saitama, Japan.
Takeshi ShimizuRIKEN Center for Sustainable Resource Science, Chemical Biology Research Group, Wako, Saitama, Japan.
Akiko OkanoRIKEN Center for Sustainable Resource Science, Chemical Biology Research Group, Wako, Saitama, Japan.
Yushi FutamuraRIKEN Center for Sustainable Resource Science, Chemical Biology Research Group, Wako, Saitama, Japan.
Shunji TakahashiRIKEN Center for Sustainable Resource Science, Natural Product Biosynthesis Research Unit, Saitama, Japan.
Hiroyuki OsadaRIKEN Center for Sustainable Resource Science, Chemical Biology Research Group, Wako, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new decaline metabolites, wakodecalines A and B, were isolated from a fungus, Pyrenochaetopsis sp. RK10-F058, by screening for structurally unique metabolites using LC/MS analysis. Their structures were determined on the basis of NMR and mass spectrometric measurements. The absolute structures were confirmed by a combination of chemical methods including chemical degradation, a modified Mosher's method and Marfey's method, and comparison of the experimental electronic CD (ECD) spectrum with calculated one. Both compounds had a cyclopentanone-fused decaline skeleton and an N-methylated amino acid moiety derived from a serine. They showed moderate antimalarial activity against the Plasmodium falciparum 3D7 strain.The Journal of Antibiotics advance online publication, 13 September 2017; doi:10.1038/ja.2017.103.

Identifiers

PMID28901329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.