ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2018
Accuracy of Various Lymph Node Staging Criteria in Rectal Cancer with Magnetic Resonance Imaging.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Apparent diffusion coefficient cannot discriminate metastatic and non-metastatic lymph nodes in rectal cancer: a meta-analysis.International journal of colorectal disease · 2021Pooled it
- Magnetic Resonance Imaging Evaluation of the Accuracy of Various Lymph Node Staging Criteria in Rectal Cancer: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2021Pooled it
- The risk of nodal disease in patients with pathological complete responses after neoadjuvant chemoradiation for rectal cancer: a systematic review, meta-analysis, and meta-regression.International journal of colorectal disease · 2019Pooled it
- Rectal cancer: a methodological approach to matching PET/MRI to histopathology.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020Trial
- Diagnostic performance of [Abdominal radiology (New York) · 2026Article
- Contrast-enhanced vs T2-weighted MRI for mesorectal nodal staging in rectal cancer.European radiology · 2026Article
- MRI Dark-Light-Dark Sign and Node Reporting Score: An Integrated Model for Predicting Lymph Node Metastasis in Rectal Cancer.Journal of clinical medicine · 2026Article
- Diagnostic and prognostic performance of MRI-based Node-RADS for regional lymph node assessment in treatment-naive rectal cancer.European radiology · 2026Article
- Radiomics' Role in Predicting Distant Metastases, Recurrence and Survival Outcome in Rectal Cancer: A Systematic Review.Cancers · 2026Review
- Selecting patients with rectal cancer for total neoadjuvant therapy based on clinical lymph node status: do we dare?Acta oncologica (Stockholm, Sweden) · 2026Article
- Deep learning model for predicting lymph node metastasis around rectal cancer based on rectal tumor core area and mesangial imaging features.BMC medical imaging · 2025Article
- A novel pN stage prediction model for resectable rectal adenocarcinoma based on preoperative MRI features and multiregional apparent diffusion coefficients.European radiology · 2025Article
- MRI radiomic study on prediction of nonenlarged lymph node metastasis of rectal cancer: reduced field-of-view versus conventional DWI.European radiology experimental · 2025Article
- Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging and Positron Emission Tomography (PET) for Distinguishing Metastatic Lymph Nodes from Nonmetastatic Among Patients with Rectal Cancer: A Systematic Review and Meta-Analysis.World journal of nuclear medicine · 2025Article
- Development and validation of machine learning-based MRI radiomics models for preoperative lymph node staging in T3 rectal cancer.Frontiers in oncology · 2025Article
- A nomogram model for predicting lymph node metastasis of rectal cancer by combining preoperative magnetic resonance imaging signs and tumour markers.Polish journal of radiology · 2025Article
- Diagnostic performance of Node-RADS score for mesorectal lymph node metastasis in rectal cancer.Abdominal radiology (New York) · 2025Article
- Preoperative scoring system for the prediction of risk of lymph node metastasis in cervical cancer.Scientific reports · 2024Article
- Novel deep learning radiomics nomogram-based multiparametric MRI for predicting the lymph node metastasis in rectal cancer: A dual-center study.Journal of cancer research and clinical oncology · 2024Article
- Diagnostic performance of Node Reporting and Data System (Node-RADS) for assessing mesorectal lymph node in rectal cancer by CT.BMC cancer · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe accuracy of pretherapeutic staging of lymph nodes (LN) in rectal cancer by MR imaging (MRI) is still limited. The aim of the study was to determine the sensitivity and specificity of different morphological criteria in nodal staging. MATERIAL AND
methodsLN were analyzed by MRI in 60 patients with rectal cancer and primary surgery. Signs of LN metastasis (cN+) were spiculated/indistinct border contour, inhomogeneous signal intensity, or LN size. The accuracy of these signs for clinical LN staging was analyzed with conclusive postoperative histological lymph node examination.
results68.3% of patients with nodal metastasis (pN+) were correctly identified by size with a cutoff value of 7.2 mm. This, however, was not inferior to the 76.7% identified using the inhomogeneous morphological signal intensity and spiculated/indistinct border contour criteria (p = 0.096). 3.3 versus 5% were overstaged, and 28.3 versus 18.3% understaged by these criteria. Sensitivities/specificities for (a) size, (b) spiculated/indistinct border contour, and (c) inhomogeneous signal intensity and spiculated/indistinct border contour were (a) 32%/94%, (b) 56%/86%, and (c) 56%/91%, respectively.
conclusionsThe accuracy of LN staging in rectal cancer was not improved by morphological criteria. These limitations suggest being reticent when recommending neoadjuvant chemoradiation merely based on preoperative positive LN staging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.