Evidence map›Paper›PMID 28900813›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2018

Assessment of acute bowel function after radiotherapy for prostate cancer: Is it accurate enough?

M Bonet, L Cayetano, M Núñez, E Jovell-Fernández, A Aguilar, Y Ribas

Abstract read
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In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Bowel dysfunction in survivors of gynaecologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M BonetDepartment of Radiation Oncology, Consorci Sanitari de Terrassa, Terrassa, Spain. bonet.marta@gmail.com.ORCID http://orcid.org/0000-0002-6417-0514
L CayetanoDepartment of Surgery, Consorci Sanitari de Terrassa, Terrassa, Spain.
M NúñezDepartment of Radiation Oncology, Consorci Sanitari de Terrassa, Terrassa, Spain.
E Jovell-FernándezDepartment of Epidemiology, Consorci Sanitari de Terrassa, Terrassa, Spain.
A AguilarDepartment of Urology, Consorci Sanitari de Terrassa, Terrassa, Spain.
Y RibasDepartment of Surgery, Consorci Sanitari de Terrassa, Terrassa, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePelvic radiotherapy for prostate cancer can be associated with bowel toxicity, which may have a significant impact on quality of life. Our aim was to assess the adequacy of the tools currently used to assess bowel symptoms after radiotherapy, including physician and patient reported outcomes. This sub-study on acute toxicity was part of a prospective trial assessing long-term bowel dysfunction. MATERIALS AND

methodsBetween February 2013 and July 2015, 75 patients with prostate cancer who received radiotherapy completed the LENT/SOMA and the EPIC questionnaires baseline and 2 weeks after the treatment. The Bristol stool scale and two additional questions on faecal urgency were added. Physicians assessed toxicity using Common Terminology Criteria for Adverse Events v.4.0. Agreement between patients and clinicians was assessed using the Cohen's κ coefficient.

resultsAcute toxicity during radiotherapy was very low. The pattern of overall bowel bother was similar before and after treatment. Faecal urgency significantly increased after radiotherapy compared to baseline but was only detected by the additional questions and not by the physicians or the patient-reported outcomes (PRO) questionnaires. Correlation between physician and PRO was poor for most symptoms.

conclusionBowel symptoms such as urgency may remain undetected by usual tools to assess toxicity after radiotherapy. Assessment of bowel toxicity should be reappraised in order to identify those patients who may have symptoms with an impact on their quality of life.

Indexed as

AgedAged, 80 and overHumansIntestine, LargeMaleMiddle AgedProstatic NeoplasmsRadiation InjuriesRadiotherapy, ConformalSurveys and QuestionnairesBowel dysfunctionFaecal urgencyProstate cancerQuality of lifeRadiotherapy

Identifiers

PMID28900813

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.