Evidence map›Paper›PMID 28900686›Full record

ArticlePsychopharmacology2017

Changes in marijuana use symptoms and emotional functioning over 28-days of monitored abstinence in adolescent marijuana users.

Joanna Jacobus, Lindsay M Squeglia, Silvia Escobar, Benjamin M McKenna, Margie Mejia Hernandez, Kara S Bagot, Charles T Taylor, Marilyn A Huestis

Abstract read
In one paragraph

Article in Psychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. The Cannabis Ask: What's a Psychiatrist to Do?Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2022
    Article
  6. Article
  7. Cannabis and Depression.Advances in experimental medicine and biology · 2021
    Review
  8. Review
  9. Cannabis cessation among youth: rates, patterns and academic outcomes in a large prospective cohort of Canadian high school students.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2020
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna JacobusVeterans Affairs San Diego Healthcare System, San Diego, CA, USA. jjacobus@ucsd.edu.
Lindsay M SquegliaDepartment of Psychiatry and Behavioral Sciences, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC, USA.
Silvia EscobarDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Benjamin M McKennaVeterans Affairs San Diego Healthcare System, San Diego, CA, USA.
Margie Mejia HernandezDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Kara S BagotDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Charles T TaylorDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Marilyn A HuestisSchool of Medicine, University of Maryland, Baltimore, MD, USA.

Funding

ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
AACAP Physician Scientist Program in Substance UseK12DA000357 · NIDA · AMERICAN ACADEMY-CHILD/ADOLESCENT PSYCH · PI Kevin M. Gray · 1998 to 2026
$29.1M
UC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: San DiegoU01AA021692 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Susan F. Tapert · 2012 to 2026
$11.8M
Clinical Scientists Training Program in Addictions at MUSCK12DA031794 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Kevin M. Gray, AIMEE L MCRAE-CLARK · 2013 to 2026
$7.2M
fMRI Cognition in Youth at Risk for Alcoholism-Diversity SupplementR01AA013419 · NIAAA · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI TAPERT, SUSAN F · 2002 to 2017
$7.1M
TRANSLATIONAL CTR ON THE CLINICAL NEUROBIOL OF CANNABIS ADDICTIONP20DA024194 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI MASON, BARBARA J · 2007 to 2010
$3.8M
Neuroscience-informed Treatment Development for Adolescent Alcohol Use DisordersK23AA025399 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SQUEGLIA, LINDSAY · 2016 to 2020
$1.0M
NCATS NIH HHS KL2 TR001444NIAAA NIH HHS K23 AA025399NIAAA NIH HHS R01 AA013419NIAAA NIH HHS U01 AA021692NIDA NIH HHS K12 DA000357NIDA NIH HHS K12 DA031794NIDA NIH HHS P20 DA024194NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041089,NIDA NIH HHS U24 DA041123
6 · The paper itself

Abstract

rationaleAdvancing marijuana prevention and intervention efforts are important given the decreasing perception of harm among adolescents and increasing marijuana legalization.

objectivesThis study evaluates how a monitored abstinence protocol may contribute to emotional functioning and changes in marijuana problems that can enhance successful outcomes for non-treatment-seeking adolescent marijuana users.

methodsAdolescent marijuana users (n = 26) and demographically matched controls (n = 30) completed 28 days of monitored abstinence confirmed by biweekly urine toxicology. Participants were given measures of emotional functioning, marijuana use symptoms, and reward sensitivity during monitored abstinence.

resultsAll participants (n = 56) completed the protocol, and 69% of marijuana users (n = 18 of 26) were confirmed abstinent for 28 days, with all users showing decreasing marijuana use. Reductions in subsyndromal depression, positive marijuana use expectancies, and poor sleep quality were observed by the end of the monitored abstinence period (n = 26, p values < .05). Marijuana users also reported more attentional impulsivity and less responsiveness to reward stimuli during the second week of abstinence compared to controls. Later age of onset of regular marijuana use and more cumulative lifetime use were associated with a greater degree of emotional change and increased recognition of the negative effects of marijuana use.

conclusionsMonitored abstinence programs may be beneficial in reducing marijuana use, subsyndromal emotional distress symptoms, and changing beliefs about marijuana use. Future prevention and intervention efforts may consider targeting reward sensitivity and impulsivity, in addition to marijuana use, expectancies, and emotional functioning.

Indexed as

EmotionsAdolescentAdolescent BehaviorCannabinoidsFemaleHumansMaleMarijuana AbuseMarijuana SmokingMarijuana UseSubstance Abuse DetectionTemperanceTime FactorsCannabinoidsAbstinenceAdolescenceDepressionMarijuana

Identifiers

PMID28900686
PMCPMC5693666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.