Evidence map›Paper›PMID 28900517›Full record

ArticleTheranostics2017

Bone-Inspired Spatially Specific Piezoelectricity Induces Bone Regeneration.

Peng Yu, Chengyun Ning, Yu Zhang, Guoxin Tan, Zefeng Lin, Shaoxiang Liu, Xiaolan Wang, Haoqi Yang, Kang Li, Xin Yi and 2 more

Abstract read
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Advanced Piezoelectric Materials, Devices, and Systems for Orthopedic Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. The Role of PEMFs on Bone Healing: An In Vitro Study.International journal of molecular sciences · 2022
    Article
  18. Article
  19. Review
  20. [Research progress on the effect of surface charge of biomaterials on bone formation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peng YuSchool of Materials Science and Engineering, Biomedical Engineering Key Laboratory of Guangdong Province, South China University of Technology, Guangzhou, 510641, China.
Chengyun NingSchool of Materials Science and Engineering, Biomedical Engineering Key Laboratory of Guangdong Province, South China University of Technology, Guangzhou, 510641, China.
Yu ZhangGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Guoxin TanInstitute of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006, China.
Zefeng LinGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Shaoxiang LiuGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Xiaolan WangGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Haoqi YangGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Kang LiGeneral Hospital of Guangzhou Military Command of PLA, Guangzhou, 510010, China.
Xin YiSchool of Materials Science and Engineering, Biomedical Engineering Key Laboratory of Guangdong Province, South China University of Technology, Guangzhou, 510641, China.
Ye ZhuDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman OK 73019, USA.
Chuanbin MaoDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman OK 73019, USA.

Funding

Virus-based nanoparticles for detecting breast cancer biomarkersR01EB021339 · NIBIB · UNIVERSITY OF OKLAHOMA · PI CAO, BINRUI · 2016 to 2019
$1.4M
Selective tumor inhibition by tumor-homing angiogenesis-suppressing nanofibersR21CA200504 · NCI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2015 to 2016
$361k
Hiring Non-toxic Virus Nanoparticles to Count Cancer Biomarker MoleculesR21CA195607 · NCI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2015 to 2016
$359k
NCI NIH HHS R21 CA195607NCI NIH HHS R21 CA200504NIBIB NIH HHS R01 EB021339
6 · The paper itself

Abstract

The extracellular matrix of bone can be pictured as a material made of parallel interspersed domains of fibrous piezoelectric collagenous materials and non-piezoelectric non-collagenous materials. To mimic this feature for enhanced bone regeneration, a material made of two parallel interspersed domains, with higher and lower piezoelectricity, respectively, is constructed to form microscale piezoelectric zones (MPZs). The MPZs are produced using a versatile and effective laser-irradiation technique in which K

Indexed as

Bone RegenerationElectricityAlkaline PhosphataseAnimalsBone and BonesCell DifferentiationCell ProliferationCells, CulturedCollagenCore Binding Factor Alpha 1 SubunitMaleMesenchymal Stem CellsMiceOsteogenesisOsteopontinRabbitsAlkaline PhosphataseCollagenCore Binding Factor Alpha 1 SubunitOsteopontinboneelectrical cuespiezoelectricitystem cells.tissue regeneration

Identifiers

PMID28900517
PMCPMC5595139

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.