Evidence map›Paper›PMID 28900515›Full record

ArticleTheranostics2017

Fluorocarbons Enhance Intracellular Delivery of Short STAT3-sensors and Enable Specific Imaging.

Valeriy Metelev, Surong Zhang, Shaokuan Zheng, Anand T N Kumar, Alexei Bogdanov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Synthesis of New Polyfluoro Oligonucleotides via Staudinger Reaction.International journal of molecular sciences · 2024
    Article
  3. Theranostics · 2021
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valeriy MetelevLaboratory of Molecular Imaging Probes, Department of Radiology, University of Massachusetts Medical School, Worcester MA.
Surong ZhangLaboratory of Molecular Imaging Probes, Department of Radiology, University of Massachusetts Medical School, Worcester MA.
Shaokuan ZhengLaboratory of Molecular Imaging Probes, Department of Radiology, University of Massachusetts Medical School, Worcester MA.
Anand T N KumarA. Martinos' Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown MA 02129 USA.
Alexei BogdanovLaboratory of Molecular Imaging Probes, Department of Radiology, University of Massachusetts Medical School, Worcester MA.

Funding

MR SIGNAL AMPLIFICATION FOR RECEPTOR IMAGINGR01EB000858 · NIBIB · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOGDANOV, ALEXEI A. · 2003 to 2022
$6.0M
Unruptured Intracranial Aneurysms: Rupture-Risk Assessment by Non-Invasive Molecular ImagingR01NS091552 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOGDANOV, ALEXEI A., GOUNIS, MATTHEW JOHN · 2015 to 2018
$2.1M
Molecular fluorescence lifetime sensor of pro-inflammatory signaling in diabetesR01DK095728 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOGDANOV, ALEXEI A. · 2014 to 2017
$1.5M
Engineering of multi-functional nucleolin-targeted nucleic acid delivery system.R21EB017980 · NIBIB · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ZHANG, SURONG · 2014 to 2015
$418k
NIBIB NIH HHS R01 EB000858NIBIB NIH HHS R21 EB017980NIDDK NIH HHS R01 DK095728NINDS NIH HHS R01 NS091552
6 · The paper itself

Abstract

Short oligonucleotide sequences are now being widely investigated for their potential therapeutic properties. The modification of oligonucleotide termini with short fluorinated residues is capable of drastically altering their behavior in complex

Indexed as

Molecular ImagingCarbocyaninesCell Line, TumorElectrophoretic Mobility Shift AssayFatty AcidsFluorocarbonsHumansIntracellular SpaceMolecular Dynamics SimulationMolecular ProbesOligodeoxyribonucleotidesPolylysineProton Magnetic Resonance SpectroscopySTAT3 Transcription FactorCarbocyaninescyanine dye 3Fatty AcidsFluorocarbonsMolecular ProbesOligodeoxyribonucleotidesperfluoroundecanoic acidPolylysineSTAT3 Transcription Factorconfocal microscopyfluorocarbonmagnetic resonance imagingoligonucleotideSTAT3.

Identifiers

PMID28900515
PMCPMC5595137

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.