Evidence map›Paper›PMID 28900252›Full record

ArticleScientific reports2017

Profiling of the metabolic transcriptome via single molecule molecular inversion probes.

Tessa de Bitter, Carlijn van de Water, Corina van den Heuvel, Carolien Zeelen, Astrid Eijkelenboom, Bastiaan Tops, Egbert Oosterwijk, Dimitar Kolev, Peter Mulders, Mark Ter Laan and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. RNA-based high-risk HPV genotyping and identification of high-risk HPV transcriptional activity in cervical tissues.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tessa de BitterDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Carlijn van de WaterDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Corina van den HeuvelDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Carolien ZeelenDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Astrid EijkelenboomDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Bastiaan TopsDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Egbert OosterwijkDept of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Dimitar KolevDept of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Peter MuldersDept of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Mark Ter LaanDept of Neurosurgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
Sanne van LithDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
William LeendersDept of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands. William.leenders@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-specific metabolic alterations are of high interest as therapeutic targets. These alterations vary between tumor types, and to employ metabolic targeting to its fullest potential there is a need for robust methods that identify candidate targetable metabolic pathways in individual cancers. Currently, such methods include

Indexed as

Gene Expression ProfilingTranscriptomeComputational BiologyEnergy MetabolismGene Expression Regulation, NeoplasticGene LibraryHigh-Throughput Nucleotide SequencingHumansNeoplasmsPolymorphism, Single NucleotideReproducibility of Results

Identifiers

PMID28900252
PMCPMC5595890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.