ArticleScientific reports2017
Functional neural changes associated with acquired amusia across different stages of recovery after stroke.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Functional neuroplasticity in chronic post-stroke aphasia following a singing intervention in a cross-over randomised trial.Scientific reports · 2025Trial
- Trial
- Post-stroke enriched auditory environment induces structural connectome plasticity: secondary analysis from a randomized controlled trial.Brain imaging and behavior · 2022Trial
- Vocal music enhances memory and language recovery after stroke: pooled results from two RCTs.Annals of clinical and translational neurology · 2020Trial
- Systematic review and meta-analysis reveal positive therapeutic effects of music in brain damage rehabilitation.Frontiers in integrative neuroscience · 2026Review
- Music and Affective Prosody after Surgical Removal of the Right Arcuate Fasciculus: A Case Study.Annals of the New York Academy of Sciences · 2025Article
- Focal Brain Lesions Causing Acquired Amusia Map to a Common Brain Network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Differential activation of a frontoparietal network explains population-level differences in statistical learning from speech.PLoS biology · 2022Article
- Neuroanatomical correlates of speech and singing production in chronic post-stroke aphasia.Brain communications · 2022Article
- Clinical and Neural Predictors of Treatment Response to Music Listening Intervention after Stroke.Brain sciences · 2021Article
- Autistic traits, resting-state connectivity, and absolute pitch in professional musicians: shared and distinct neural features.Molecular autism · 2019Article
- Cognitive and neural mechanisms underlying the mnemonic effect of songs after stroke.NeuroImage. Clinical · 2019Article
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain damage causing acquired amusia disrupts the functional music processing system, creating a unique opportunity to investigate the critical neural architectures of musical processing in the brain. In this longitudinal fMRI study of stroke patients (N = 41) with a 6-month follow-up, we used natural vocal music (sung with lyrics) and instrumental music stimuli to uncover brain activation and functional network connectivity changes associated with acquired amusia and its recovery. In the acute stage, amusic patients exhibited decreased activation in right superior temporal areas compared to non-amusic patients during instrumental music listening. During the follow-up, the activation deficits expanded to comprise a wide-spread bilateral frontal, temporal, and parietal network. The amusics showed less activation deficits to vocal music, suggesting preserved processing of singing in the amusic brain. Compared to non-recovered amusics, recovered amusics showed increased activation to instrumental music in bilateral frontoparietal areas at 3 months and in right middle and inferior frontal areas at 6 months. Amusia recovery was also associated with increased functional connectivity in right and left frontoparietal attention networks to instrumental music. Overall, our findings reveal the dynamic nature of deficient activation and connectivity patterns in acquired amusia and highlight the role of dorsal networks in amusia recovery.
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