Evidence map›Paper›PMID 28900210›Full record

ArticleScientific reports2017

Alterations of Brain Functional Architecture Associated with Psychopathic Traits in Male Adolescents with Conduct Disorder.

Weidan Pu, Qiang Luo, Yali Jiang, Yidian Gao, Qingsen Ming, Shuqiao Yao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  3. The Cognitive-Affective Social Processing and Emotion Regulation (CASPER) model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  4. Infectious diseases and childhood disruptive behavior disorders: a reappraisal.Frontiers in cellular and infection microbiology · 2026
    Article
  5. Article
  6. Article
  7. Impaired salience network switching in psychopathy.Behavioural brain research · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Weidan PuMedical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, P.R. China.
Qiang LuoSchool of Life Sciences, Fudan University, Shanghai, P.R. China.
Yali JiangMedical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, P.R. China.
Yidian GaoMedical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, P.R. China.
Qingsen MingMedical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, P.R. China.
Shuqiao YaoMedical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, P.R. China. shuqiaoyao@163.com.
Central South University · CNSecond Xiangya Hospital of Central South University · CNShanghai Center for Brain Science and Brain-Inspired Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychopathic traits of conduct disorder (CD) have a core callous-unemotional (CU) component and an impulsive-antisocial component. Previous task-driven fMRI studies have suggested that psychopathic traits are associated with dysfunction of several brain areas involved in different cognitive functions (e.g., empathy, reward, and response inhibition etc.), but the relationship between psychopathic traits and intrinsic brain functional architecture has not yet been explored in CD. Using a holistic brain-wide functional connectivity analysis, this study delineated the alterations in brain functional networks in patients with conduct disorder. Compared with matched healthy controls, we found decreased anti-synchronization between the fronto-parietal network (FPN) and default mode network (DMN), and increased intra-network synchronization within the frontothalamic-basal ganglia, right frontoparietal, and temporal/limbic/visual networks in CD patients. Correlation analysis showed that the weakened FPN-DMN interaction was associated with CU traits, while the heightened intra-network functional connectivity was related to impulsivity traits in CD patients. Our findings suggest that decoupling of cognitive control (FPN) with social understanding of others (DMN) is associated with the CU traits, and hyper-functions of the reward and motor inhibition systems elevate impulsiveness in CD.

Indexed as

Brain MappingQuantitative Trait, HeritableAdolescentBrainCase-Control StudiesConduct DisorderConnectomeHumansImage Processing, Computer-AssistedImpulsive BehaviorMagnetic Resonance ImagingMale

Identifiers

PMID28900210
PMCPMC5595864
OpenAlexW2751855746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.