Evidence map›Paper›PMID 28900116›Full record

ArticleScientific reports2017

Response induced in Mycoplasma gallisepticum under heat shock might be relevant to infection process.

Ivan Butenko, Anna Vanyushkina, Olga Pobeguts, Daria Matyushkina, Sergey Kovalchuk, Alexey Gorbachev, Nicolay Anikanov, Gleb Fisunov, Vadim Govorun

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in microbiology · 2026
    Article
  4. Article
  5. Article
  6. The Monitoring ofAntibiotics (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Comparative Analysis ofFrontiers in genetics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivan ButenkoLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.ORCID 0000-0003-4473-587X
Anna VanyushkinaLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.
Olga PobegutsLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.
Daria MatyushkinaLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia. d.matyushkina@gmail.com.ORCID 0000-0001-9535-5792
Sergey KovalchukLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.
Alexey GorbachevLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.
Nicolay AnikanovLaboratory of Proteomics, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, 117997, Russia.
Gleb FisunovLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.
Vadim GovorunLaboratory of Proteomic Analysis, Federal Research and Clinical Centre of Physical-Chemical Medicine, Moscow, 119435, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the fact the term "proteome" was proposed to characterize a set of proteins in one of mycoplasma species, proteome response to various exposures in this bacteria are still obscure. Commonly, authors studying proteomic response on perturbation models in mycoplasmas use single approach and do not confirm their findings by alternative methods. Consequently, the results of proteomic analysis should be validated by complementary techniques. In this study we utilized three complementary approaches (SWATH, MRM, 2D-DIGE) to assess response of Mycoplasma gallisepticum under heat stress on proteomic level and combined these findings with metabolic response and the results of transcriptional profiling. We divide response into two modes - one is directly related to heat stress and other is triggered during heat stress, but not directly relevant to it. The latter includes accumulation of ATP and shedding of antigens. Both of these phenomena may be relevant to evasion of host's immune system and dissemination during mycoplasmosis in vivo.

Indexed as

Heat-Shock ResponseAdenosine TriphosphateComputational BiologyHemagglutination TestsMetabolomeMetabolomicsMycoplasma gallisepticumMycoplasma InfectionsTemperatureTerpenesAdenosine TriphosphateTerpenes

Identifiers

PMID28900116
PMCPMC5595898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.