ArticleScientific reports2017
Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-α.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Biophoton emission promotes the modern scientific utilization of medicinal plants: from theoretical integration to research applications.Frontiers in chemistry · 2025Review
- Open quantum systems theory of ultraweak ultraviolet photon emissions: Revisiting Gurwitsch's onion experiment as a prototype for quantum biology.Computational and structural biotechnology journal · 2024Review
- Unique algorithm for the evaluation of embryo photon emission and viability.Scientific reports · 2024Article
- Exploring Intercellular Dynamics: Ultra-Weak Biophoton Emission as a Novel Indicator of Altered Cell Functions and Disease in Oligospermia Mice.Journal of lasers in medical sciences · 2023Article
- Modelling biophoton emission kinetics based on the initial intensity value in Helianthus annuus plants exposed to different types of stress.Scientific reports · 2022Article
- Stochastic light concentration from 3D to 2D reveals ultraweak chemi- and bioluminescence.Scientific reports · 2021Article
- Quantifying Biofield Therapy through Biophoton Emission in a Cellular Model.Journal of scientific exploration : a publication of the Society for Scientific Exploration · 2020Article
- Mechanism of the Formation of Electronically Excited Species by Oxidative Metabolic Processes: Role of Reactive Oxygen Species.Biomolecules · 2019Review
- Triplet Excited Carbonyls and Singlet Oxygen Formation During Oxidative Radical Reaction in Skin.Frontiers in physiology · 2018Article
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Authors and funding
4 authors.
Funding
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Abstract
Cells spontaneously emit photons in the UV to visible/near-infrared range (ultra-weak photon emission, UPE). Perturbations of the cells' state cause changes in UPE (evoked UPE). The aim of the present study was to analyze the evoked UPE dynamics of cells caused by two types of cell perturbations (stressors): (i) a cell culture medium change, and (ii) application of the pro-inflammatory cytokine tumor necrosis factor alpha (TNF-α). Four types of human cell lines were used (squamous cell carcinoma cells, A431; adenocarcinomic alveolar basal epithelial cells, A549; p53-deficient keratinocytes, HaCaT, and cervical cancer cells, HeLa). In addition to the medium change, TNF-α was applied at different concentrations (5, 10, 20, and 40 ng/mL) and UPE measurements were performed after incubation times of 0, 30, 60, 90 min, 2, 5, 12, 24, 48 h. It was observed that (i) the change of cell culture medium (without added TNF-α) induces a cell type-specific transient increase in UPE with the largest UPE increase observed in A549 cells, (ii) the addition of TNF-α induces a cell type-specific and dose-dependent change in UPE, and (iii) stressed cell cultures in general exhibit oscillatory UPE changes.
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